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  1. Article

    Open Access

    Osteoarthritis: pathogenic signaling pathways and therapeutic targets

    Osteoarthritis (OA) is a chronic degenerative joint disorder that leads to disability and affects more than 500 million population worldwide. OA was believed to be caused by the wearing and tearing of articula...

    Qing Yao, **aohao Wu, Chu Tao, Weiyuan Gong… in Signal Transduction and Targeted Therapy (2023)

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  2. Article

    Open Access

    Kindlin-2 loss in condylar chondrocytes causes spontaneous osteoarthritic lesions in the temporomandibular joint in mice

    The progressive destruction of condylar cartilage is a hallmark of the temporomandibular joint (TMJ) osteoarthritis (OA); however, its mechanism is incompletely understood. Here, we show that Kindlin-2, a key ...

    Yumei Lai, Wei Zheng, Minghao Qu… in International Journal of Oral Science (2022)

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