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Article
Brain lesions: is there a role for internist?
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Article
Open AccessGenetic aspects underlying the normocalcemic and hypercalcemic phenotypes of primary hyperparathyroidism
Hypercalcemic primary hyperparathyroidism (PHPT) is a common endocrine disorder that has been very well characterized. In contrast, many aspects of normocalcemic primary hyperparathyroidism (NPHPT) such as nat...
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Article
Open AccessOpioid-Induced Constipation in Real-World Practice: A Physician Survey, 1 Year Later
Opioid-induced constipation (OIC) is the most common adverse effect of opioid therapy, but it is underdiagnosed and undertreated. Last year, a survey among Italian healthcare providers revealed important diffe...
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Article
Open AccessImpact and Consequences of Opioid-Induced Constipation: A Survey of Patients
Opioids are a valuable tool to help achieve control of pain. However, opioid-induced constipation (OIC) is an important limitation of treatment with this class of drugs.
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Article
Open AccessCorrection to: What to Do and What Not to Do in the Management of Opioid-Induced Constipation: A Choosing Wisely Report
The original article can be found online.
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Article
Open AccessWhat to Do and What Not to Do in the Management of Opioid-Induced Constipation: A Choosing Wisely Report
Despite the essential utility of opioids for the clinical management of pain, opioid-induced constipation (OIC) remains an important obstacle in clinical practice. In patients, OIC hinders treatment compliance...
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Article
A Challenging Case of Tumor-Induced Osteomalacia: Pathophysiological and Clinical Implications
We investigated the usefulness of fibroblast growth factor 23 (FGF23) intraoperative assay to monitor tumor resection in patients with oncogenic osteomalacia. A 33-year-old man with 5 years’ history of lumbar ...
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Article
Circulating tumor cells in high-risk nonmetastatic colorectal cancer
The identification of patients at higher risk of recurrence after primary colorectal cancer resection is currently one of the challenges facing medical oncologists. Circulating tumor cell (CTC) may represent a...
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Article
Circulating tumor cells in young and elderly patients with colorectal cancer: “lupus et agnus”
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Article
Circulating tumor cells in young and elderly patients with colorectal cancer: “lupus et agnus”
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Article
Effects of Donepezil,Galantamine and Rivastigmine in 938 Italian Patients with Alzheimer’s Disease
Background: Acetylcholinesterase inhibitors (AChEIs) have been used to improve cognitive status and disability in patients with mild to moderate Alzheimer’s disease (AD). However, while the effic...
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Article
Decreased nocturnal systolic blood pressure fall in older subjects with depression
Depressed subjects have a two-fold increased risk of CV events than non-depressed ones. Altered blood pressure (BP) circadian profile may be one mechanism underlying this association. We studied 135 elderly su...
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Article
Induction of multidrug resistance proteins in lymphocytes from patients with arthritic disorders
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Article
Role of 99mTc-Sestamibi scintimammography by SPEM camera in the management of breast cancer in the elderly
The incidence of breast cancer in the elderly is 10 fold higher than in the population younger than 65 years. Moreover, in this segment of the population there are not defined clear practice guidelines regardi...
