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  1. Article

    Open Access

    Comparison of long-term clinical outcomes of bioabsorbable polymer versus durable polymer drug-eluting stents: a systematic review and meta-analysis

    One million individuals in the USA die from acute myocardial infarction (MI), which currently affects 3 million people globally. The available data about the early and late outcomes of both biodegradable polym...

    Abdur Rehman, Ifra Eeman Ahmed, Ahmed Nouman, Rabia Irfan in The Egyptian Heart Journal (2024)

  2. No Access

    Article

    Frontiers in Acute Pain Management: Emerging Concepts in Pain Pathways and the Role of VX-548 as a Novel NaV1.8 Inhibitor: A Narrative Review

    Despite ongoing research into alternative postsurgical pain treatments, opioids remain widely used analgesics regardless of associated adverse effects, including dependence and overdose, as demonstrated throug...

    Alan D. Kaye, Erin S. Everett, Arianna M. Lehuquet in Current Pain and Headache Reports (2024)

  3. No Access

    Article

    Immune Competence and Pain: A Narrative Review

    This review aims to summarize current knowledge on the pathophysiology of pain and the role of neuro-immune crosstalk in the development of acute and chronic pain (CP). Specifically, the review focuses on the ...

    Stefano Coaccioli, Piercarlo Sarzi-Puttini in Current Pain and Headache Reports (2024)

  4. Article

    Open Access

    Dexketoprofen Trometamol and Tramadol Hydrochloride Fixed-Dose Combination in Moderate to Severe Acute Low Back Pain: A Phase IV, Randomized, Parallel Group, Placebo, Active-Controlled Study (DANTE)

    Dexketoprofen/tramadol 25/75 mg (DKP/TRAM) is a fixed-dose combination of a cyclooxygenase inhibitor and opioid receptor agonist. To better understand the efficacy and safety of DKP/TRAM in the treatment of mo...

    Giustino Varrassi, Magdi Hanna, Stefano Coaccioli, Paolo Fabrizzi in Pain and Therapy (2024)

  5. Article

    Open Access

    Innovative Applications of Telemedicine and Other Digital Health Solutions in Pain Management: A Literature Review

    Since the COVID-19 pandemic, healthcare systems are facing extraordinary challenges. Our approaches to medicine have changed and created a whole new generation of people who have chronic pain. Various medical ...

    Salah N. El-Tallawy, Joseph V. Pergolizzi, Ingrid Vasiliu-Feltes in Pain and Therapy (2024)

  6. Article

    Open Access

    Incorporation of “Artificial Intelligence” for Objective Pain Assessment: A Comprehensive Review

    Pain is a significant health issue, and pain assessment is essential for proper diagnosis, follow-up, and effective management of pain. The conventional methods of pain assessment often suffer from subjectivit...

    Salah N. El-Tallawy, Joseph V. Pergolizzi, Ingrid Vasiliu-Feltes in Pain and Therapy (2024)

  7. Article

    Open Access

    Microbial Symphony: Exploring the Role of the Gut in Osteoarthritis-Related Pain. A Narrative Review

    One of the most common musculoskeletal disorders, osteoarthritis (OA), causes worldwide disability, morbidity, and poor quality of life by degenerating articular cartilage, modifying subchondral bone, and infl...

    Alberto Corriero, Mariateresa Giglio, Rossana Soloperto in Pain and Therapy (2024)

  8. Article

    Open Access

    Correction: Efficacy and safety of ciprofol versus propofol for induction and maintenance of general anesthesia: a systematic review and meta-analysis

    Muhammad Hudaib, Hurais Malik in Journal of Anesthesia, Analgesia and Criti… (2024)

  9. Article

    Open Access

    Efficacy and safety of ciprofol versus propofol for induction and maintenance of general anesthesia: a systematic review and meta-analysis

    Propofol has been the gold standard for anesthesia induction and maintenance due to its rapid onset and favorable pharmacokinetic properties. However, the search for alternative agents with improved safety and...

    Muhammad Hudaib, Hurais Malik in Journal of Anesthesia, Analgesia and Criti… (2024)

  10. Article

    Open Access

    Gut Microbiota Modulation and Its Implications on Neuropathic Pain: A Comprehensive Literature Review

    Neuropathic pain (NP) is a chronic pain disorder arising from somatosensory nervous system impairment. Extensive evidence supports the notion that the gut microbiota (GM) is crucial in maintaining human health...

    Alberto Corriero, Mariateresa Giglio, Francesco Inchingolo in Pain and Therapy (2024)

  11. Article

    Open Access

    Arts Therapy and Its Implications in Chronic Pain Management: A Narrative Review

    Chronic nonmalignant pain is recognized as a complex, dynamic, phenomenological interplay between biological, psychological, and social factors that are individual to the person suffering from it. Therefore, i...

    Jaroslava Raudenská, Veronika Šteinerová, Šárka Vodičková in Pain and Therapy (2023)

  12. Article

    Open Access

    Correction to: Delphi-Based Expert Consensus Statements for the Management of Percutaneous Radiofrequency Neurotomy in the Treatment of Lumbar Facet Joint Syndrome

    Felice Occhigrossi, Roberta Carpenedo, Matteo Luigi Giuseppe Leoni in Pain and Therapy (2023)

  13. Article

    Open Access

    Low Back Pain and Radiofrequency Denervation of Facet Joint: Beyond Pain Control—A Video Recording

    Chronic low back pain is often due to L5S1 instability resulting in facet joint syndrome. Patients suffering from low back pain may also have a gait pattern characterized by a reduced speed and a shorter, asym...

    Mariateresa Giglio, Giacomo Farì, Angela Preziosa, Alberto Corriero in Pain and Therapy (2023)

  14. Article

    Open Access

    Correction to: Chronic Non-cancer Pain Management in a Tertiary Pain Clinic Network: a Retrospective Study

    Roberto Latina, Giustino Varrassi, Ettore Di Biagio, Diana Giannarelli in Pain and Therapy (2023)

  15. Article

    Open Access

    Delphi-Based Expert Consensus Statements for the Management of Percutaneous Radiofrequency Neurotomy in the Treatment of Lumbar Facet Joint Syndrome

    A modified Delphi strategy was implemented for obtaining recommendations that could be useful in the management of percutaneous radiofrequency treatment of lumbar facet joint syndrome, as the literature on the...

    Felice Occhigrossi, Roberta Carpenedo, Matteo Luigi Giuseppe Leoni in Pain and Therapy (2023)

  16. Article

    Open Access

    Critical Appraisal of Current Acute LBP Management and the Role of a Multimodal Analgesia: A Narrative Review

    Acute low back pain (LBP) stands as a leading cause of activity limitation and work absenteeism, and its associated healthcare expenditures are expected to become substantial when acute LBP develops into a chr...

    Magdi Hanna, Serge Perrot, Giustino Varrassi in Pain and Therapy (2023)

  17. Article

    What Do We Need to Know About Rising Rates of Idiopathic Pulmonary Fibrosis? A Narrative Review and Update

    The most common type of idiopathic interstitial pneumonia is idiopathic pulmonary fibrosis (IPF), an irreversible, progressive disorder that has lately come into question for possible associations with COVID-1...

    Joseph V. Pergolizzi Jr., Jo Ann LeQuang, Marco Varrassi in Advances in Therapy (2023)

  18. Article

    Open Access

    Chronic Non-cancer Pain Management in a Tertiary Pain Clinic Network: a Retrospective Study

    Chronic pain is a distressing condition that should be treated in specialized pain clinics. Pain clinics offer a holistic, evidence-based approach, including pharmacological, complementary, and invasive treatm...

    Roberto Latina, Giustino Varrassi, Ettore Di Biagio, Diana Giannarelli in Pain and Therapy (2023)

  19. Article

    Open Access

    Risk of COVID-19 Diagnosis and Hospitalisation in Patients with Osteoarthritis or Back Pain Treated with Ibuprofen Compared to Other NSAIDs or Paracetamol: A Network Cohort Study

    We aimed to investigate whether ibuprofen use, compared with other non-selective non-steroidal anti-inflammatory drugs (ns-NSAIDs), cyclooxygenase-2 inhibitors (COX-2i) or paracetamol, increases the risk of co...

    Junqing **e, James T. Brash, Cigdem Turkmen, Stefan Driessen, Giustino Varrassi in Drugs (2023)

  20. No Access

    Chapter

    Endoscopy in Pain Therapy

    Pain represents one of the most important burdens and challenges in medicine. Pain management has largely evolved in the last decades. The introduction into the market of new technologies and devices has influ...

    Stefano Meloncelli, Marco Divizia, Martina Rekatsina in Endoscopy of the Spine (2023)

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