Skip to main content

and
  1. No Access

    Article

    Impact of ABCC2 haplotypes on transcriptional and posttranscriptional gene regulation and function

    ABCC2 (MRP2) is an important export pump, expressed at tissue barriers. The genetic variants −24C>T, 1249G>A and 3972C>T are leading to inter-individual differences of bioavailability of various endogenous and...

    S Laechelt, E Turrini, A Ruehmkorf, W Siegmund, I Cascorbi in The Pharmacogenomics Journal (2011)

  2. No Access

    Article

    Persistierendes Fieber unter zielgerichteter antituberkulotischer Therapie

    Ein 37-jähriger Inder wurde mit persistierendem Husten und hohem Fieber stationär aufgenommen. Umfassende Untersuchungen sicherten die Diagnose einer Lungentuberkulose. Die kalkulierte antituberkulöse Therapie...

    Dr. B. Koch, S. Gläser, W. Siegmund, C.-D. Heidecke, D. Walther, R. Ewert in Der Pneumologe (2009)

  3. No Access

    Article

    ABSTRACTS: ISoP Annual Conference ‘Joining Forces for Managing Risks’ Liège, Belgium 11–13 October, 2006

    S. Schmiedl, J. Szymanski, M. Rottenkolber, B. Drewelow, G. Haase in Drug Safety (2006)

  4. No Access

    Article

    ABSTRACTS: ISoP Annual Conference ‘Joining Forces for Managing Risks’ Liège, Belgium 11–13 October, 2006

    P. A. Thuermann, S. Haack, U. Werner, W. Siegmund, K. May, J. Szymanski in Drug Safety (2006)

  5. Article

    223 Placental Transfer of the Protease Inhibitor Nelfinavir in the Dual in Vitro Placenta Perfusion Model

    Intro: The protease inhibitor nelfinavir is a common drug for treatment of HIV in pregnancy. Pairs of serum samples of maternal vein - and umbilical cord blood show very low levels of nelfinavir in umbilical c...

    K Linnemann, D Mehltretter, K May, N Siebert, M Kurowski, H K Kroemer in Pediatric Research (2005)

  6. No Access

    Article

    Arzneimitteltransporter

    W. Siegmund, I. Cascorbi, W. Weitschies, H. Kroemer in Der Internist (2003)

  7. No Access

    Chapter

    Schmerztherapie

    Es war schon immer die wichtigste Aufgabe des Arztes, Leiden vom Patienten abzuwenden oder zumindest zu lindern. So umfaßt der Kernbereich der anästhesiologischen Tätigkeit die Bekämpfung von Schmerzen.

    W. Siegmund, P. M. Osswald in Komplikationen in der Anästhesie (1997)

  8. No Access

    Article

    Kinetics of propiverine as assessed by radioreceptor assay in poor and extensive metabolizers of debrisoquine

    A pharmacokinetic study with 30 mg propiverine p.o. was performed in healthy volunteers (10 males, 6 females, age 36–56 years, body weight 55–100 kg, body height 162–184 cm, Broca index 0.96–1.19). 8 of them w...

    C. Müller, W. Siegmund, R. Huupponen in European Journal of Drug Metabolism and Ph… (1993)

  9. No Access

    Article

    Level- and line-crossing in forward scattering and selective reflection in a transverse magnetic field

    LC-experiments in forward scattering and selective reflection are mostly performed in a longitudinal magnetic field. We have extended the investigations to a transverse field receiving the following results. T...

    W. Siegmund, A. Scharmann in Zeitschrift für Physik A Atoms and Nuclei (1976)

  10. No Access

    Article

    Excitation of orientation and alignment by unpolarized light

    The experimental arrangements to generate all tensor components of orientation and alignment are outlined. For different cases calculated and measured curves are shown. Whereas in the case of alignment the con...

    W. Oberheim, W. Siegmund in Zeitschrift für Physik B Condensed Matter (1975)