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Chapter
Vacuum Technology
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Article
Near-tetraploid acute myeloid leukemias: an EGIL retrospective study of 25 cases
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Article
CD87 (urokinase-type plasminogen activator receptor), function and pathology in hematological disorders: a review
The analysis of CD87 (urokinase-type plasminogen activator receptor – uPAR) expression has a potential role in the diagnostic or prognostic work-up of several hematological malignancies, particularly acute leu...
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Article
Analysis of SH2D1A mutations in patients with severe Epstein-Barr virus infections, Burkitt's lymphoma, and Hodgkin's lymphoma
Mutations or deletions in the SH2D1A (src homology 2 domain protein 1A) gene result in a severe immunodeficiency called X-linked lymphoproliferative (XLP) disease. XLP is primarily characterized by a defective...
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Article
Establishment of radioactive astatine and iodine uptake in cancer cell lines expressing the human sodium/iodide symporter
The sodium/iodide symporter (NIS) has been recognized as an attractive target for radioiodine-mediated cancer gene therapy. In this study we investigated the role of human NIS for cellular uptake of the high ...
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Article
Influence of rhTSH on [18F]fluorodeoxyglucose uptake by differentiated thyroid carcinoma
The influence of serum TSH levels on fluorine-18 fluorodeoxyglucose (FDG) uptake by recurrences or metastases of differentiated thyroid carcinomas has not yet been clarified. The aim of this study was to asce...
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Article
Monitoring isotretinoin therapy in thyroid cancer using 18F-FDG PET
Treatment with isotretinoin (13-cis-retinoic acid, 13-cis-RA) is a recent additional option in advanced, otherwise intractable differentiated thyroid cancers. The aim of this study was to evaluate fluorine-18 fl...
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Article
Biokinetics and imaging with the somatostatin receptor PET radioligand 68Ga-DOTATOC: preliminary data
Somatostatin (SMS) scintigraphy is widely used for the detection and staging of neuroendocrine tumours. Because of its superior imaging properties, there is growing interest in the use of positron emission tom...
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Article
CD20 antibody (C2B8)-induced apoptosis of lymphoma cells promotes phagocytosis by dendritic cells and cross-priming of CD8+ cytotoxic T cells
C2B8 (Rituximab, MabThera) is a chimeric mouse/human monoclonal antibody (mAb) directed against the human B cell-restricted cell surface antigen CD20 which is used as an alternative medication in the treatment...
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Article
Culture requirements for induction of dendritic cell differentiation in acute myeloid leukemia
Peripheral blood mononuclear cells (PBMCs) from 15 newly diagnosed acute myeloid leukemia (AML) patients were cultured in fetal calf serum-free media supplemented with either granulocyte/macrophage-colony sti...
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Chapter and Conference Paper
Interdependence of Draft Tube and Tailwater Flow in Bulb Turbine Power Plants
The advantages of bulb turbines result mainly from smaller dimensions and better efficiencies in comparison to the vertical-axis Kaplan type used earlier. Bulb turbines are characterized by high values of spec...
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Article
Molecular characterization of CD34+ human hematopoietic progenitor cells
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Chapter and Conference Paper
Flow Cytometric Analysis of Intracellular Myeloperoxidase and Lactoferrin in Leukemia Diagnosis
The immunological characterization of leukemic blast cells in terms of their lineage commitment and differentiation stage has so far mainly been based on the analysis of surface marker molecules. Mainly for te...
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Chapter and Conference Paper
Myeloid-Associated Antigen Expression in Childhood Acute Lymphoblastic Leukemia
Coexpression of myeloid-associated antigens has been demonstrated in several studies on acute lymphoblastic leukemia (ALL). The proportion of cases with this aberrant antigen expression (myA+ ALL) ranged from 5% ...
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Chapter and Conference Paper
Poster
Das deutsche Tierschutzgesetz schreibt ebenso wie das EG-Recht vor, daß bei der Entscheidung, ob Tierversuche durchgeführt werden dürfen, zu prüfen ist. ob der verfolgte Zweck nicht durch andere Methoden oder ...
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Article
Phenotypic analysis of functionally associated molecules on peripheral blood and synovial fluid monocytes from arthritis patients
Surface expression of 16 different membrane molecules was analyzed in peripheral blood and synovial fluid monocytes from patients with rheumatoid arthritis and reactive arthritis compared to controls. The most...
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Chapter and Conference Paper
Immunological Phenoty** of Blood and Bone Marrow Cells From Patients with Myelodysplastic Syndromes
Since the discovery of the hybridoma technique monoclonal antibodies (MoAb) have been widely used in various fields of medicine [1], and immunological phenty** using MoAbs has become a routine technology for...
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Article
Ratio of complement receptor over Fc-receptor III expression: A sensitive parameter to monitor granulocyte-macrophage colony-stimulating factor effects on neutrophils
In vitro activation of human granulocytes leads to altered expression of distinct surface antigens. Compared with the changes observed with classic activating reagents such as the phorbol ester PMA similar, bu...
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Chapter and Conference Paper
Association of GP40/CD7+ Acute Myeloblastic Leukemia and Chromosome 5 Aberrations
Immunological investigation of human leukemias revealed conservation of lineage specificity in the majority of cases. However, deviations of maturation-linked phenotype (i.e., asynchronous differentiation comp...
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Chapter and Conference Paper
Behandlung von steroidresistenten Abstoßungsreaktionen nach Transplantation solider Organe mit einem monoklonalen Anti-CD 4 Antikörper
Nach Transplantation solider Organe sind Abstoßungsreaktionen trotz verbes serter prophylaktischer Immunsuppression immer noch eine bedeutsame und häufige Komplikation. Insbesonders jene Abstoßungen, bei denen...
