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  1. Article

    Open Access

    Xanthine dehydrogenase downregulation promotes TGFβ signaling and cancer stem cell-related gene expression in hepatocellular carcinoma

    Xanthine dehydrogenase (XDH), a rate-limiting enzyme involved in purine metabolism, has an essential role in inflammatory cascades. Researchers have known for decades that XDH activity is decreased in some can...

    G-L Chen, T Ye, H-L Chen, Z-Y Zhao, W-Q Tang, L-S Wang, J-L **a in Oncogenesis (2017)

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