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Obesity-associated T-cell and macrophage activation improve partly after a lifestyle intervention
The relation between low-grade inflammation and metabolic dysfunction in obesity is not fully explored.
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Open AccessXXIV World Allergy Congress 2015
A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts
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Open AccessLack of common TCRA and TCRB clonotypes in CD8+/TCRαβ+ T-cell large granular lymphocyte leukemia: a review on the role of antigenic selection in the immunopathogenesis of CD8+ T-LGL
Clonal CD8+/T-cell receptor (TCR)αβ+ T-cell large granular lymphocyte (T-LGL) proliferations constitute the most common subtype of T-LGL leukemia. Although the etiology of T-LGL leukemia is largely unknown, it ha...
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Open AccessMast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)
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Open AccessThe neonatal Fc receptor is expressed by human lymphocytes
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Open AccessEfficacy of adalimumab in sarcoidosis
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Open AccessInflammatory T-lymphocyte proliferation in morbid obesity
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BMI1 as oncogenic candidate in a novel TCRB-associated chromosomal aberration in a patient with TCRγδ+ T-cell acute lymphoblastic leukemia
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Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes
The BIOMED-2 multiplex polymerase chain reaction (PCR) tubes for analysis of immunoglobulin and T-cell receptor (TCR) gene rearrangements have recently been introduced as a reliable and easy tool for clonality...
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Article
CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes
The t(10;11)(p13;q14–21) is found in T-ALL and acute myeloid leukemia and fuses CALM (Clathrin-Assembly protein-like Lymphoid-Myeloid leukaemia gene) to AF10. In order to gain insight into the transcriptional con...
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Purity for clarity: the need for purification of tumor cells in DNA microarray studies
It is now well established that gene expression profiling using DNA microarrays can provide novel information about various types of hematological malignancies, which may lead to identification of novel diagno...
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Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL
T-cell acute lymphoblastic leukemia (T-ALL) is associated with chromosomal aberrations characterized by juxtaposition of proto-oncogenes to T-cell receptor gene loci (TCR), resulting in the deregulated transcript...
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275 Epithelial Repair in The Preterm Lung is Decreased in The Early Phase of Bronchopulmonary Dysplasia
Background: In the early phases bronchopulmonary dysplasia (BPD) is characterized by epithelial and endothelial damage and inflammation. A recent study showed an absent or decreased concentration of keratinocyte ...