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  1. No Access

    Article

    Obesity-associated T-cell and macrophage activation improve partly after a lifestyle intervention

    The relation between low-grade inflammation and metabolic dysfunction in obesity is not fully explored.

    I. J. B. van der Zalm, E. S. van der Valk, V. L. Wester in International Journal of Obesity (2020)

  2. Article

    Open Access

    XXIV World Allergy Congress 2015

    A1 Pirfenidone inhibits TGF-b1-induced extracellular matrix production in nasal polyp-derived fibroblasts

    Heung-Man Lee, Il-Ho Park, Jae-Min Shin in World Allergy Organization Journal (2016)

  3. Article

    Open Access

    Lack of common TCRA and TCRB clonotypes in CD8+/TCRαβ+ T-cell large granular lymphocyte leukemia: a review on the role of antigenic selection in the immunopathogenesis of CD8+ T-LGL

    Clonal CD8+/T-cell receptor (TCR)αβ+ T-cell large granular lymphocyte (T-LGL) proliferations constitute the most common subtype of T-LGL leukemia. Although the etiology of T-LGL leukemia is largely unknown, it ha...

    Y Sandberg, M J Kallemeijn, W A Dik, D Tielemans in Blood Cancer Journal (2014)

  4. Article

    Open Access

    Mast cells are major contributors to the pathophysiology of Graves’ Ophthalmopathy (GO)

    L Van Steensel, D Paridaens, P M van Hagen in Journal of Translational Medicine (2010)

  5. Article

    Open Access

    The neonatal Fc receptor is expressed by human lymphocytes

    K van Bilsen, J Bastiaans, W A Dik, E F De Haas in Journal of Translational Medicine (2010)

  6. Article

    Open Access

    Efficacy of adalimumab in sarcoidosis

    LSJ Kamphuis, W K Lam-Tse, W A Dik, J Bastiaans in Journal of Translational Medicine (2010)

  7. Article

    Open Access

    Inflammatory T-lymphocyte proliferation in morbid obesity

    K Van der Weerd, P M van Hagen, W A Dik, B S Schrijver in Journal of Translational Medicine (2010)

  8. No Access

    Article

    BMI1 as oncogenic candidate in a novel TCRB-associated chromosomal aberration in a patient with TCRγδ+ T-cell acute lymphoblastic leukemia

    N S D Larmonie, W A Dik, H B Beverloo, E R van Wering, J J M van Dongen in Leukemia (2008)

  9. No Access

    Article

    Human T-cell lines with well-defined T-cell receptor gene rearrangements as controls for the BIOMED-2 multiplex polymerase chain reaction tubes

    The BIOMED-2 multiplex polymerase chain reaction (PCR) tubes for analysis of immunoglobulin and T-cell receptor (TCR) gene rearrangements have recently been introduced as a reliable and easy tool for clonality...

    Y Sandberg, B Verhaaf, E J van Gastel-Mol, I L M Wolvers-Tettero, J de Vos in Leukemia (2007)

  10. No Access

    Article

    CALM-AF10+ T-ALL expression profiles are characterized by overexpression of HOXA and BMI1 oncogenes

    The t(10;11)(p13;q14–21) is found in T-ALL and acute myeloid leukemia and fuses CALM (Clathrin-Assembly protein-like Lymphoid-Myeloid leukaemia gene) to AF10. In order to gain insight into the transcriptional con...

    W A Dik, W Brahim, C Braun, V Asnafi, N Dastugue, O A Bernard, J J M van Dongen in Leukemia (2005)

  11. No Access

    Article

    Purity for clarity: the need for purification of tumor cells in DNA microarray studies

    It is now well established that gene expression profiling using DNA microarrays can provide novel information about various types of hematological malignancies, which may lead to identification of novel diagno...

    D de Ridder, C E van der Linden, T Schonewille, W A Dik, M J T Reinders in Leukemia (2005)

  12. No Access

    Article

    Disruption of the BCL11B gene through inv(14)(q11.2q32.31) results in the expression of BCL11B-TRDC fusion transcripts and is associated with the absence of wild-type BCL11B transcripts in T-ALL

    T-cell acute lymphoblastic leukemia (T-ALL) is associated with chromosomal aberrations characterized by juxtaposition of proto-oncogenes to T-cell receptor gene loci (TCR), resulting in the deregulated transcript...

    G K Przybylski, W A Dik, J Wanzeck, P Grabarczyk, S Majunke, J I Martin-Subero in Leukemia (2005)

  13. Article

    275 Epithelial Repair in The Preterm Lung is Decreased in The Early Phase of Bronchopulmonary Dysplasia

    Background: In the early phases bronchopulmonary dysplasia (BPD) is characterized by epithelial and endothelial damage and inflammation. A recent study showed an absent or decreased concentration of keratinocyte ...

    L J I Zimmermann, M A Versnel, B A E Naber, D J M Janssen, W A Dik in Pediatric Research (2004)