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  1. Article

    Open Access

    Natural history of X-linked hypohidrotic ectodermal dysplasia: a 5-year follow-up study

    X-linked hypohidrotic ectodermal dysplasia (XLHED) is caused by pathogenic variants of the gene EDA disrupting the prenatal development of ectodermal derivatives. Cardinal symptoms are hypotrichosis, lack of teet...

    Sigrun Wohlfart, Ralph Meiller, Johanna Hammersen in Orphanet Journal of Rare Diseases (2020)

  2. Article

    Open Access

    Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2)

    Here we investigated the role of NFAT-interacting protein (NIP)-45, an Interleukin (IL)-4 inducing Transcription Factor, and its impact on the differentiation of Group 2 Innate -Lymphoid -Cells (ILC2s) in the ...

    Sonja Koch, Lisa Knipfer, Julia Kölle, Hooman Mirzakhani, Anna Graser in Scientific Reports (2019)

  3. Article

    Open Access

    Successful eradication of newly acquired MRSA in six of seven patients with cystic fibrosis applying a short-term local and systemic antibiotic scheme

    In individuals with cystic fibrosis (CF), colonization with methicillin-resistant Staphylococcus aureus (MRSA) was reported to be associated with a deterioration of pulmonary disease as reflected by an accelerate...

    Alexander Kiefer, Christian Bogdan, Volker O. Melichar in BMC Pulmonary Medicine (2018)

  4. Article

    Open Access

    Correction: Corrigendum: IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma

    Scientific Reports 7: Article number: 43426; published online: 06 March 2017; updated: 24 August 2017. This Article contains an error in the Author Information section, where the following statement was omitte...

    Isabella Hentschke, Anna Graser, Volker O. Melichar, Alexander Kiefer in Scientific Reports (2017)

  5. Article

    Open Access

    IL-33/ST2 immune responses to respiratory bacteria in pediatric asthma

    Here we investigated the relationship between local bacterial colonization and anti-bacterial immune responses in pre-school asthmatic and control children within the EU-wide study PreDicta. In this cohort of ...

    Isabell Hentschke, Anna Graser, Volker O. Melichar, Alexander Kiefer in Scientific Reports (2017)