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  1. Article

    Open Access

    Gestational diabetes mellitus, prenatal maternal depression, and risk for postpartum depression: an Environmental influences on Child Health Outcomes (ECHO) Study

    Prior research has demonstrated bidirectional associations between gestational diabetes mellitus (GDM) and perinatal maternal depression. However, the association between GDM, prenatal depression, and postpart...

    Lauren C. Shuffrey, Maristella Lucchini, Santiago Morales… in BMC Pregnancy and Childbirth (2022)

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  2. Article

    Open Access

    Late first trimester circulating microparticle proteins predict the risk of preeclampsia < 35 weeks and suggest phenotypic differences among affected cases

    We hypothesize that first trimester circulating micro particle (CMP) proteins will define preeclampsia risk while identifying clusters of disease subtypes among cases. We performed a nested case–control analys...

    Thomas F. McElrath, David E. Cantonwine, Kathryn J. Gray… in Scientific Reports (2020)

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  3. Article

    Open Access

    Early-pregnancy transcriptome signatures of preeclampsia: from peripheral blood to placenta

    Several studies have linked maternal asthma, excess BMI, and low vitamin D status with increased risk of Preeclampsia (PE) development. Given prior evidence in the literature and our observations from the subj...

    Aishwarya P. Yadama, Enrico Maiorino, Vincent J. Carey… in Scientific Reports (2020)

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  4. Article

    Open Access

    Targeted deletion of NFAT-Interacting-Protein-(NIP) 45 resolves experimental asthma by inhibiting Innate Lymphoid Cells group 2 (ILC2)

    Here we investigated the role of NFAT-interacting protein (NIP)-45, an Interleukin (IL)-4 inducing Transcription Factor, and its impact on the differentiation of Group 2 Innate -Lymphoid -Cells (ILC2s) in the ...

    Sonja Koch, Lisa Knipfer, Julia Kölle, Hooman Mirzakhani, Anna Graser… in Scientific Reports (2019)

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  5. No Access

    Article

    Applications of metabolomics in the study and management of preeclampsia: a review of the literature

    Preeclampsia represents a major public health burden worldwide, but predictive and diagnostic biomarkers are lacking. Metabolomics is emerging as a valuable approach to generating novel biomarkers whilst incre...

    Rachel S. Kelly, Rachel T. Giorgio, Bo L. Chawes, Natalia I. Palacios… in Metabolomics (2017)

  6. No Access

    Article

    Integration of metabolomic and transcriptomic networks in pregnant women reveals biological pathways and predictive signatures associated with preeclampsia

    Preeclampsia is a leading cause of maternal and fetal mortality worldwide, yet its exact pathogenesis remains elusive.

    Rachel S. Kelly, Damien C. Croteau-Chonka, Amber Dahlin, Hooman Mirzakhani… in Metabolomics (2016)