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Article
The Fontan Udenafil Exercise Longitudinal Trial: Subgroup Analysis
The Pediatric Heart Network’s Fontan Udenafil Exercise Longitudinal (FUEL) Trial (Mezzion Pharma Co. Ltd., NCT 02741115) demonstrated improvements in some measures of exercise capacity and in the myocardial pe...
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Article
Open AccessGenetic and clinical variables act synergistically to impact neurodevelopmental outcomes in children with single ventricle heart disease
Recent large-scale sequencing efforts have shed light on the genetic contribution to the etiology of congenital heart defects (CHD); however, the relative impact of genetics on clinical outcomes remains less u...
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Article
Exercise Capacity and Predictors of Performance After Fontan: Results from the Pediatric Heart Network Fontan 3 Study
Impaired exercise following Fontan is a surrogate of morbidity. Single-center longitudinal data exist, but there is a lack of contemporary multi-center data. Ramp cycle ergometry was re-performed in consented ...
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Article
Factors Associated with Serum B-Type Natriuretic Peptide in Infants with Single Ventricles
Data regarding the value of B-type natriuretic peptide (BNP) measurements in infants with a single-ventricle (SV) physiology are lacking. This analysis aimed to describe the BNP level changes in infants with a...
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Article
The Relationship of Patient Medical and Laboratory Characteristics to Changes in Functional Health Status in Children and Adolescents After the Fontan Procedure
Despite hypothesized concerns about deterioration beginning in adolescence, longitudinal data and associated factors regarding standardized assessment of physical functioning are not available for Fontan patie...
