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Chapter
Population-Based Cancer Registries: A Data Stream to Help Build an Evidence-Based Cancer Policy for Europe and for European Countries
A population-based cancer registry (PBCR) is an ongoing surveillance system to collect, store, manage, analyse and disseminate information on the occurrence of cancer in a defined population. Modern cancer reg...
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Chapter
Social Inequities in Cancer: Why Develop Scientific Research?
The observation of social inequities in health is well documented, and their reduction is a major political issue at the national and community levels. Social inequities in health do not arise from biological ...
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Chapter
Overview of Main Mechanisms Involved in Social Disparities in Cancer Incidence and Prognosis
Explanatory mechanisms of the social determination of cancer occurrence and prognosis involve proximal and distal factors, as first suggested by Dahlgren and Whitehead. The application of this general model en...
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Chapter
Disparities in Cancer Survival in Adults in Europe: The CONCORD Programme
Wide European differences in cancer survival have been highlighted for decades. The most up-to-date world-wide trends in survival are available from the CONCORD programme. In Europe, data were provided for CON...
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Chapter
Social Disparities in Cancer Incidence: Methodological Considerations
Background: We present statistical models to describe the geographical distribution of the incidence of a cancer site on a fine spatial scale and the part of geographical variation that can be related to the s...
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Chapter
Social Disparities in Cancer Incidence Among Adults in Europe
Numerous epidemiological studies published over the past two decades have provided further evidence of an association between socioeconomic status and incidence of all of the most common cancers in European co...
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Article
Endocrine treatment and incidence of relapse in women with oestrogen receptor-positive breast cancer in Europe: a population-based study
Endocrine therapy (ET) is the mainstream adjuvant treatment for ER-positive breast cancer (BC). We analysed 9293 ER-positive BC patients diagnosed in nine European countries in 2009–2013 to investigate how com...
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Article
Open AccessLong-term work retention after treatment for cancer: a systematic review and meta-analysis
Almost half of people diagnosed with cancer are working age. Survivors have increased risk of unemployment, but little is known about long-term work retention. This systematic review and meta-analysis assessed...
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Article
Reasons for low cervical cancer survival in new accession European Union countries: a EUROCARE-5 study
With better access to early diagnosis and appropriate treatment, cervical cancer (CC) burden decreased in several European countries. In Eastern European (EE) countries, which accessed European Union in 2004, ...
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Article
Explaining variation in quality of breast cancer care and its impact: a nationwide population-based study from Slovenia
To assess and explain variation in quality of care in breast cancer patients and estimate its impact on disease outcome.
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Article
Open AccessDevelopment and validation of a prognostic model to predict the prognosis of patients who underwent chemotherapy and resection of pancreatic adenocarcinoma: a large international population-based cohort study
Pancreatic cancer (PaC) remains extremely lethal worldwide even after resection. PaC resection rates are low, making prognostic studies in resected PaC difficult. This large international population-based stud...
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Article
Open AccessStratified survival of resected and overall pancreatic cancer patients in Europe and the USA in the early twenty-first century: a large, international population-based study
The prognosis of pancreatic cancer (PaC) strongly varies across different stages and age groups, which has unfortunately not been well recorded in the literature. This international population-based study aime...
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Article
Filgrastim-alone versus pegylated filgrastim-alone for autologous peripheral blood stem cells mobilization in newly diagnosed multiple myeloma patients
Autologous hematopoietic stem cell transplantation (aHSCT) is the recommended standard upfront treatment for transplant eligible myeloma patients. Considering possible complications related to chemotherapy–cyt...
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Article
Squamous cell carcinoma of unknown primary tumor metastatic to neck nodes: role of elective irradiation
In patients with squamous cell carcinoma (SCC) metastases to neck lymph nodes and unknown primary tumor, the role of elective irradiation of uninvolved neck and potential mucosal primary sites is yet to be det...
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Article
Incidence trends in head and neck squamous cell carcinoma in Slovenia, 1983–2009: role of human papillomavirus infection
An increase in the incidence of oropharyngeal squamous cell carcinoma (OPSCC) was observed in several population-based registries and has been attributed to human papillomavirus (HPV) infection. In the presen...
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Article
HER2 in Gastric Cancer: An Immunohistochemical Study on Tissue Microarrays and the Coressponding Whole-Tissue Sections with a Supplemental Fish Study
Since focal HER2 expression is an issue in GC, TMA construction from the paraffin-embedded surgically-obtained tissue may not reflect its real status. The aim of this study was to assess the HER2 status in tis...
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Article
Cardiac toxicity of high-dose cyclophosphamide and melphalan in patients with multiple myeloma treated with tandem autologous hematopoietic stem cell transplantation
Tandem autologous hematopoetic stem cell transplantation (HSCT) is an effective treatment in patients with multiple myeloma (MM). Patients receive high-dose cyclophosphamide (CY) followed by two myeloablative ...
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Article
Cardiac Toxicity of High-Dose Cyclophosphamide in Patients with Multiple Myeloma Undergoing Autologous Hematopoietic Stem Cell Transplantation
High-dose cyclophosphamide is a well-known mobilization regimen in patients with multiple myeloma undergoing autologous hematopoietic stem cell transplantation. Highly differing rates of cardiac complications ...