Skip to main content

and
  1. Protocol

    Targeted Locus Amplification and Haploty**

    Targeted locus amplification (TLA) allows for the detection of all genetic variation (including structural variation) in a genomic region of interest. As TLA is based on proximity ligation, variants can be lin...

    Juliet W. Lefferts, Vera Boersma, Marne C. Hagemeijer, Karima Hajo in Haploty** (2023)

  2. No Access

    Article

    MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection

    MAD2L2 regulates DNA repair at deprotected telomeres and at ionizing-radiation-induced double-stranded DNA breaks by inhibiting resection of the 5′ ends; the ends are thus shunted into the non-homologous end-j...

    Vera Boersma, Nathalie Moatti, Sandra Segura-Bayona, Marieke H. Peuscher in Nature (2015)