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Protocol
Targeted Locus Amplification and Haploty**
Targeted locus amplification (TLA) allows for the detection of all genetic variation (including structural variation) in a genomic region of interest. As TLA is based on proximity ligation, variants can be lin...
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Article
MAD2L2 controls DNA repair at telomeres and DNA breaks by inhibiting 5′ end resection
MAD2L2 regulates DNA repair at deprotected telomeres and at ionizing-radiation-induced double-stranded DNA breaks by inhibiting resection of the 5′ ends; the ends are thus shunted into the non-homologous end-j...