4 Result(s)

Article

Author Correction: Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation

Bianca de Jonckheere, Ferdinand Kollotzek, Patrick Münzer… in Nature Cardiovascular Research (2023)

Article

Critical shifts in lipid metabolism promote megakaryocyte differentiation and proplatelet formation

During megakaryopoiesis, megakaryocytes (MKs) undergo cellular morphological changes with strong modification of membrane composition and lipid signaling. Here, we adopt a lipid-centric multiomics approach to ...

Bianca de Jonckheere, Ferdinand Kollotzek, Patrick Münzer… in Nature Cardiovascular Research (2023)

Article

Foudroyant cerebral venous (sinus) thrombosis triggered through CLEC-2 and GPIIb/IIIa dependent platelet activation

Cerebral venous (sinus) thrombosis (CVT) is an unusual manifestation of venous thrombosis causing severe neurological impairment and seizures^1,2. Molecular mechanisms underlying CVT, potentially involving patholo...

David Stegner, Vanessa Göb, Viola Krenzlin, Sarah Beck… in Nature Cardiovascular Research (2022)

Article

Infarct growth precedes cerebral thrombosis following experimental stroke in mice

Ischemic stroke is among the leading causes of disability and death worldwide. In acute ischemic stroke, successful recanalization of occluded vessels is the primary therapeutic aim, but even if it is achieved...

Vanessa Göb, Maximilian G. Voll, Lena Zimmermann, Katherina Hemmen… in Scientific Reports (2021)