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  1. No Access

    Article

    Characterisation of explanted endothelial cells from mouse aorta: electrophysiology and Ca2+ signalling

    We describe here the isolation and primary culture of endothelial cells from mouse aorta ("primary explant technique"). These cells provide an excellent model for functional studies in transgenic mice. The pr...

    S.H. Suh, R. Vennekens, V.G. Manolopoulos, M. Freichel, U. Schweig… in Pflügers Archiv (1999)

  2. No Access

    Chapter

    High-Voltage Activated Ca2+ Channel

    Calcium channels are part of the signal system which is vital for intercellular communication in higher multicellular organisms. They transduce electrical or hormonal signals into a chemical second messenger, ...

    F. Hofmann, M. Biel, E. Bosse, R. Hullin, P. Ruth, A. Welling… in GTPases in Biology II (1993)

  3. No Access

    Chapter and Conference Paper

    The Structure of the Skeletal and Nonskeletal Muscle Calcium Channel

    A number of fundamental biological processes such as mobility, secretion, and neurotransmission are regulated by a change in the cytosolic calcium concentration. The cytosolic calcium concentration is raised f...

    F. Hofmann, P. Ruth, T. Schneider, J. Felbel… in Molecular Mechanisms of Hormone Action (1989)

  4. No Access

    Chapter and Conference Paper

    Biochemistry and Physiology of Cardiac Calcium Channels

    The voltage-dependent slow calcium channel allows the passive movement of calcium across the plasma membrane of a variety of excitable cells and regulates thereby directly or indirectly the cytosolic calcium c...

    F. Hofmann, V. Flockerzi, J. Oeken, P. Ruth in Neurobiochemistry (1985)

  5. No Access

    Article

    Injection of catalytic subunit of cAMP-dependent protein kinase into isolated cardiac myocytes

    Cyclic adenosine 3′,5′-monophosphate (cAMP) or the free catalytic subunit (C) of the cAMP-dependent protein kinase were pressure injected into single guinea pig ventricular cells. The following results were ob...

    G. Brum, V. Flockerzi, F. Hofmann, W. Osterrieder, W. Trautwein in Pflügers Archiv (1983)

  6. No Access

    Article

    Injection of isolated subunits of cAMP-dependent protein kinase II into single adult cardiac myocytes modulates the slow Ca++ inward current

    W. Osterrieder, G. Brum, J. Hescheler, W. Trautwein, V. Flockerzi… in Pflügers Archiv (1982)