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Article
Health-related quality of life and treatment preferences in adolescents with type 1 diabetes. The VIPKIDS study
A multi-centre, observational, cross-sectional study was carried out to determine whether the health-related quality of life (HRQOL) of adolescents with type 1 diabetes is affected by different insulin treatme...
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Article
Establishing glycaemic control with continuous subcutaneous insulin infusion in children and adolescents with type 1 diabetes: experience of the PedPump Study in 17 countries
To assess the use of paediatric continuous subcutaneous infusion (CSII) under real-life conditions by analysing data recorded for up to 90 days and relating them to outcome.
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Article
Permanent diabetes mellitus in the first year of life
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Article
Permanent diabetes mellitus in the first year of life
Aims/hypothesis. The pathogenesis of permanent diabetes mellitus diagnosed early in life is heterogeneous and, in most cases, not known. We aimed at identifying markers differentiating between no...
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Article
High prevalence of glucokinase mutations in Italian children with MODY. Influence on glucose tolerance, first-phase insulin response, insulin sensitivity and BMI
Aims/hypothesis. The aim of this study was to assess the prevalence of glucokinase gene mutations in Italian children with MODY and to investigate genotype/phenotype correlations of the mutants.
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Article
Large incidence variation of Type I diabetes in central-southern Italy 1990–1995: lower risk in rural areas
Aims/hypothesis. To evaluate the relation between the incidence of childhood Type I (insulin-dependent) diabetes mellitus and the degree of urbanization in the central-southern part of Italy. Met...
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Article
This letter was forwarded to Drs. E.Ghigo, E. Bartolotta, E. Imperiale, J. Bellone, G. Cardinale, G. Aimaretti, M.R. Valetto, V. Cherubini, M. Maccario, D. Cocchi and F. Camanni whose reply follows
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Article
Glucagon stimulates GH secretion after intramuscular but not intravenous administration. Evidence against the assumption that glucagon per se has a GH-releasing activity
In order to verify the true GH-releasing effect of glucagon and to explain the mechanism underlying this effect, we studied the effect of glucagon (GLU, 1 mg) administered either iv or im on both basal and GHR...
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Article
Pulsatile secretion of thyrotropin in children
To examine pulsatile TSH secretion, serum TSH was determined every 30 min for 24 h in eight short normal prepubertal children (3 males and 5 females, age 4.0–12.6 yr). All children exhibited a clear circadian ...
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Article
Low dose orally administered arginine is able to enhance both basal and growth hormone-releasing hormone-induced growth hormone secretion in normal short children
Aim of this study was to verify whether arginine (ARG), which likely inhibits hypothalamic somatostatin release, has an enhancing effect on the GHRH-induced GH rise, even when administered orally at low dose. ...
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Article
RING CHROMOSOME 5 IN A CHILD WITH SEVERE GROWTH RETARDATION
We report the fourth case known of ring chromosome 5 with phenotype resembling that of the “ring syndrome”. A female child of healthy, unrelated, Italian parents, was referred for diagnosis at 36 months of age...
