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  1. Article

    Open Access

    Heart failure, recurrent vascular events and death in patients with ischemic stroke—results of the MonDAFIS study

    Heart failure (HF) is associated with poor outcome after stroke, but data from large prospective trials are sparse.

    Serdar Tütüncü, Manuel C. Olma, Claudia Kunze in Internal and Emergency Medicine (2024)

  2. Article

    Open Access

    Lipoprotein(a) serum concentrations in children in relation to body mass index, age and sex

    Lipoprotein(a) (Lp(a)) is an inherited risk factor for atherosclerotic cardiovascular disease (ASCVD). Limited data exist on Lp(a) values in children. We aimed to evaluate whether Lp(a) concentrations in youth...

    Paulina E. Stürzebecher, Konstantin L. Uttinger, Mandy Vogel in Pediatric Research (2024)

  3. Article

    Open Access

    Novel Insights into the Management of Patients with Very High Cardiovascular Risk Eligible for PCSK9 Inhibitor Treatment: Baseline Findings from the PERI-DYS Study

    The PERI-DYS study aims to characterize two groups of patients with dyslipidaemia at very high CV risk: PCSK9i receivers and patients qualifying for but not receiving PCSK9i.

    Ulrich Laufs, Andreas L. Birkenfeld, Uwe Fraass in Cardiovascular Drugs and Therapy (2024)

  4. Article

    Open Access

    LDL cholesterol target attainment in cardiovascular high- and very-high-risk patients with statin intolerance: a simulation study

    The inability to tolerate sufficient doses of statins, statin intolerance (SI), contributes to the non-achievement of guideline-recommended low-density lipoprotein cholesterol (LDL-C) treatment targets. Patien...

    Julius L. Katzmann, Paulina E. Stürzebecher, Silvia Kruppert in Scientific Reports (2024)

  5. No Access

    Article

    Replik zum Leserbrief bezüglich der Stellungnahme von Rauch et al. (2023) zum Leitfaden der Arzneimittelkommission der Deutschen Ärzteschaft (AkdÄ)

    Prof. Dr. med. Bernhard Rauch, Jana Boer, Frank Edelmann, Stephan Gielen in Die Kardiologie (2023)

  6. No Access

    Article

    Atherosklerotische Veränderungen als Teil eines natürlichen Alterungsprozesses?

    Von Vertretern der Arzneimittelkommission der deutschen Ärzteschaft (AkdÄ) wurde kürzlich ein aktualisierter Leitfaden zur „Medikamentösen Cholesterinsenkung zur Vorbeugung kardiovaskulärer Ereignisse“ veröffentl...

    Prof. Dr. med. Bernhard Rauch, Jana Boer, Frank Edelmann, Stephan Gielen in Die Kardiologie (2023)

  7. Article

    Open Access

    Physical exercise as a treatment for persisting symptoms post-COVID infection: review of ongoing studies and prospective randomized controlled training study

    No evidence-based treatment is available for patients with persisting symptoms post-COVID-19 infection. We hypothesized that physical exercise may represent a safe and effective treatment option for post-COVID.

    Alexander Kogel, Moritz Machatschek, Ronja Scharschmidt in Clinical Research in Cardiology (2023)

  8. Article

    Open Access

    Independent external validation of a stroke recurrence score in patients with embolic stroke of undetermined source

    Embolic stroke of undetermined source (ESUS) accounts for a substantial proportion of ischaemic strokes. A stroke recurrence score has been shown to predict the risk of recurrent stroke in patients with ESUS b...

    Thies Ingwersen, Manuel C. Olma, Eckhard Schlemm in Neurological Research and Practice (2023)

  9. No Access

    Article

    Kardiovaskuläre Pharmakotherapie im Alter

    Kardiovaskuläre Erkrankungen stellen die häufigste Ursache für Behinderung und Tod dar. Evidenzbasierte Pharmakotherapie ist die Basis zur erfolgreichen Therapie der Volkskrankheiten Hypertonie, Herzinsuffizie...

    Prof. Dr. Martin Schulz, Dietmar Trenk, Ulrich Laufs in Herz (2023)

  10. Article

    Open Access

    Extent of routine diagnostic cardiac work-up at certified German stroke units participating in the prospective MonDAFIS study

    About 25% of all ischaemic strokes are related to cardio-embolism, most often due to atrial fibrillation (AF). Little is known about the extent and standardization of routine cardiac diagnostic work-up at cert...

    Manuel C. Olma, Serdar Tütüncü, Ulrike Grittner in Neurological Research and Practice (2023)

  11. Article

    Open Access

    Not obtaining a medication the first time it is prescribed: primary non-adherence to cardiovascular pharmacotherapy

    Primary medication non-adherence describes the situation when a first prescription for a new medication is never filled. Primary non-adherence is an important, yet understudied aspect of reduced effectiveness ...

    Martin Schulz, Ulrich Laufs in Clinical Research in Cardiology (2023)

  12. Article

    Open Access

    Native T1 map** for the diagnosis of cardiac amyloidosis in patients with left ventricular hypertrophy

    Cardiac magnetic resonance (CMR) with parametric map** can improve the characterization of myocardial tissue. We studied the diagnostic value of native T1 map** to detect cardiac amyloidosis in patients wi...

    Daniel Lavall, Nicola H. Vosshage, Romy Geßner in Clinical Research in Cardiology (2023)

  13. No Access

    Article

    Reply to: Apolipoprotein C3 induces inflammasome activation only in its delipidated form

    Stephen Zewinger, Jochen Reiser, Vera Jankowski, Dalia Alansary in Nature Immunology (2023)

  14. Article

    Open Access

    Use of fixed-dose combination antihypertensives in Germany between 2016 and 2020: an example of guideline inertia

    The 2018 European Society of Cardiology (ESC)/European Society of Hypertension (ESH) guidelines for the management of hypertension highlight the importance of fixed-dose combinations (FDC) for the treatment of...

    Felix Mahfoud, Marita Kieble, Salka Enners in Clinical Research in Cardiology (2023)

  15. No Access

    Article

    Hypercholesterolemia diagnosis, treatment patterns and target achievement in patients with acute coronary syndromes in Germany

    Patients who experience an acute coronary syndrome (ACS) are at high risk of further cardiovascular events. Long-term treatment of cardiovascular risk factors, such as hyperlipidemia, is critical to prevent pr...

    Anselm K. Gitt, Klaus G. Parhofer, Ulrich Laufs in Clinical Research in Cardiology (2023)

  16. No Access

    Article

    Erhalt von Leistungsfähigkeit und Lebensqualität bei chronischer Herzinsuffizienz (Teil 3)

    Die Endpunkte großer klinischer Interventionsstudien in der Herzinsuffizienz umfassen meist die Zahl der Krankenhausaufnahmen und die kardiovaskuläre Mortalität. Patienten mit Herzinsuffizienz leiden jedoch au...

    Prof. Dr. Dr. med. Stephan von Haehling, Michael Arzt, Wolfram Doehner in Die Kardiologie (2023)

  17. No Access

    Living Reference Work Entry In depth

    Fettstoffwechselstörungen: Hypercholesterinämie

    Die große klinische Bedeutung der Hypercholesterinämie liegt in ihrer kausalen Rolle für die Atherosklerose, der zugrunde liegenden Pathologie für die Mehrheit der Myokardinfarkte, der ischämischen Schlaganfäl...

    Ulrich Laufs in DGIM Innere Medizin

  18. No Access

    Living Reference Work Entry In depth

    Herz und Gehirn

    Erkrankungen des Gehirns (z. B. der Schlaganfall) haben häufig kardiale Ursachen. Kardiologische Erkrankungen (z. B. die Herzinsuffizienz) können zu Veränderungen der Gehirnfunktion führen. Umgekehrt können ps...

    Rolf Wachter, Ulrich Laufs in Klinische Kardiologie

  19. No Access

    Chapter

    Herz und Gehirn

    Erkrankungen des Gehirns (z. B. der Schlaganfall) haben häufig kardiale Ursachen. Kardiologische Erkrankungen (z. B. die Herzinsuffizienz) können zu Veränderungen der Gehirnfunktion führen. Umgekehrt können ps...

    Rolf Wachter, Ulrich Laufs in Klinische Kardiologie (2023)

  20. No Access

    Article

    Moderne Lipidsenker – ein Mittel gegen das Problem der Unterversorgung?

    Ein erhöhtes Low-density-Lipoprotein-Cholesterin (LDL-C) gehört zu den wichtigsten modifizierbaren kardiovaskulären Risikofaktoren. Trotz potenter Kombinationstherapien werden die LDL-C-Zielwerte bei vielen Ho...

    Dr. med. Julius L. Katzmann, Ulrich Laufs in Die Innere Medizin (2022)

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