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  1. No Access

    Article

    Global probabilistic annotation of metabolic networks enables enzyme discovery

    A new global annotation strategy combines sequence identity and genomic context to provide probabilities for all metabolic assignments in a given species. Application of this method leads to multiple new annot...

    Germán Plata, Tobias Fuhrer, Tzu-Lin Hsiao, Uwe Sauer… in Nature Chemical Biology (2012)

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    Article

    Automatic policing of biochemical annotations using genomic correlations

    Errors in functional annotations can cause significant problems in later research. A new method to identify misannotations by analyzing the genomic context correlations corrects these errors, such as in the re...

    Tzu-Lin Hsiao, Olga Revelles, Lifeng Chen, Uwe Sauer… in Nature Chemical Biology (2010)