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Article
Identification of a novel stress-responsive gene Hi95 involved in regulation of cell viability
cDNA microarray hybridization was used in an attempt to identify novel genes participating in cellular responses to prolonged hypoxia. One of the identified novel genes, designated Hi95 shared significant homo...
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Article
Highly variable incidence of cystic fibrosis and different mutation distribution among different Jewish ethnic groups in Israel
The incidence of cystic fibrosis (CF) and the frequency of disease-causing mutations varies among different ethnic and geographic populations. The Jewish population around the world is comprised of two major e...
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Article
Extended haplotype analysis of cystic fibrosis mutations and its implications for the selective advantage hypothesis
The major cystic fibrosis (CF) mutation, ΔF508, is associated with one haplotype (B) determined by the two polymorphic markers, XV2C and KM19. This haplotype is rare (15%) among non-ΔF chromosomes. Its frequen...