-
Article
Open AccessImpact of the COVID-19 pandemic on COPD exacerbations in Japanese patients: a retrospective study
Various infection control measures implemented during the coronavirus disease (COVID-19) pandemic have reduced the number of respiratory infections, which are the most common cause of chronic obstructive pulmo...
-
Article
Open AccessSETD1A protects from senescence through regulation of the mitotic gene expression program
SETD1A, a Set1/COMPASS family member maintaining histone-H3-lysine-4 (H3K4) methylation on transcriptionally active promoters, is overexpressed in breast cancer. Here, we show that SETD1A supports mitotic process...
-
Article
Open AccessSETD1A modulates cell cycle progression through a miRNA network that regulates p53 target genes
Expression of the p53-inducible antiproliferative gene BTG2 is suppressed in many cancers in the absence of inactivating gene mutations, suggesting alternative mechanisms of silencing. Using a shRNA screen target...
-
Article
Long-term survival of adrenal metastasis from non-small cell lung cancer
Long-term survival of patients who undergo surgical resection of isolated adrenal metastasis from non-small cell lung cancer (NSCLC) has been reported. In these patients, primary lung cancers were generally re...
-
Article
Alternative splicing of CD44 mRNA by ESRP1 enhances lung colonization of metastatic cancer cell
In cancer metastasis, various environmental stressors attack the disseminating cells. The successful colonization of cancer cells in secondary sites therefore requires the ability of the cells to avoid the con...
