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Correction to: A literature review and novel theoretical approach on the optical properties of whole blood
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Open AccessMisinterpretation of solid sphere equivalent refractive index measurements and smallest detectable diameters of extracellular vesicles by flow cytometry
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Open AccessBayesian analysis of depth resolved OCT attenuation coefficients
Optical coherence tomography (OCT) is an optical technique which allows for volumetric visualization of the internal structures of translucent materials. Additional information can be gained by measuring the r...
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Open AccessEstimation of microvascular perfusion after esophagectomy: a quantitative model of dynamic fluorescence imaging
Most common complications of esophagectomy stem from a perfusion deficiency of the gastric conduit at the anastomosis. Fluorescent tracer imaging allows intraoperative visualization of tissue perfusion. Quanti...
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Open AccessDeep learning for automatic Gleason pattern classification for grade group determination of prostate biopsies
Histopathologic grading of prostate cancer using Gleason patterns (GPs) is subject to a large inter-observer variability, which may result in suboptimal treatment of patients. With the introduction of digitiza...
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Open AccessThree-dimensional histopathological reconstruction of bladder tumours
Histopathological analysis is the cornerstone in bladder cancer (BCa) diagnosis. These analysis suffer from a moderate observer agreement in the staging of bladder cancer. Three-dimensional reconstructions hav...
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Open AccessLimitations of Weight Velocity Analysis by Commercial Computer Program Growth Analyser Viewer Edition
Commercial software package “Growth Analyser Viewer Edition” (“GAVE”) aims to document, monitor and analyze growth and development in children and adolescents. Although its clinical and scientific use is wides...
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Open AccessCan we predict necrosis intra-operatively? Real-time optical quantitative perfusion imaging in surgery: study protocol for a prospective, observational, in vivo pilot study
Compromised perfusion as a result of surgical intervention causes a reduction of oxygen and nutrients in tissue and therefore decreased tissue vitality. Quantitative imaging of tissue perfusion during reconstr...
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Open AccessOCT Amplitude and Speckle Statistics of Discrete Random Media
Speckle, amplitude fluctuations in optical coherence tomography (OCT) images, contains information on sub-resolution structural properties of the imaged sample. Speckle statistics could therefore be utilized i...
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Open AccessQuantitative blood flow velocity imaging using laser speckle flowmetry
Laser speckle flowmetry suffers from a debated quantification of the inverse relation between decorrelation time (τc) and blood flow velocity (V), i.e. 1/τc = αV. Using a modified microcirculation imager (integra...
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Open AccessFluorescence characteristics of human Barrett tissue specimens grafted on chick chorioallantoic membrane
To improve (pre)malignant lesion identification in Barrett’s esophagus (BE), recent research focuses on new developments in fluorescence imaging and spectroscopy to enhance tissue contrast. Our aim was to vali...
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Open AccessThe efficacy and safety of irreversible electroporation for the ablation of renal masses: a prospective, human, in-vivo study protocol
Electroporation is a novel treatment technique utilizing electric pulses, traveling between two or more electrodes, to ablate targeted tissue. The first in human studies have proven the safety of IRE for the a...
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Side branch healing patterns of the Tryton dedicated bifurcation stent: a 1-year optical coherence tomography follow-up study
The bare-metal Tryton Side Branch (SB) Stent™ (Tryton Medical, Durham, NC, USA) is used with a drug-eluting stent (DES) in the main branch (MB) to treat bifurcation lesions. It is argued that a drug-eluting Tr...
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Open AccessA literature review and novel theoretical approach on the optical properties of whole blood
Optical property measurements on blood are influenced by a large variety of factors of both physical and methodological origin. The aim of this review is to list these factors of influence and to provide the r...
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Open AccessHow the blood pool properties at onset affect the temporal behavior of simulated bruises
The influence of initial blood pool properties on the temporal behavior of bruises is currently unknown. We addressed this important issue by utilizing three typical classes of bruises in our three-layered fin...
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Optical Coherence Tomography
Seventy percent of our body is made up of water. For that reason, radiation based medical imaging techniques operate in spectral regions where water absorption is low (Fig. 18.1, left panel). Well known modali...
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Pulsed Laser Tissue Interaction
Pulsed lasers, by virtue of their ability to deliver energy in a spatially and temporally confined fashion, are able to micromachine biological tissues. The clinical success of pulsed laser treatment, however,...
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Open Access3D finite compartment modeling of formation and healing of bruises may identify methods for age determination of bruises
Simulating the spatial and temporal behavior of bruises may identify methods that allow accurate age determination of bruises to assess child abuse. We developed a numerical 3D model to simulate the spatial ki...
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Open AccessApoptosis- and necrosis-induced changes in light attenuation measured by optical coherence tomography
Optical coherence tomography (OCT) was used to determine optical properties of pelleted human fibroblasts in which necrosis or apoptosis had been induced. We analysed the OCT data, including both the scatterin...
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Open AccessReview of methodological developments in laser Doppler flowmetry
Laser Doppler flowmetry is a non-invasive method of measuring microcirculatory blood flow in tissue. In this review the technique is discussed in detail. The theoretical and experimental developments to improv...
