10 Result(s)

Article

Extracellular Vesicles to Predict Outcomes After Transcatheter Aortic Valve Implantation – a Prospective, Multicenter Cohort Study

Transcatheter aortic valve implantation (TAVI) is an established treatment for aortic stenosis (AS) in patients at intermediate and high surgical risk. Circulating extracellular vesicles (EVs) are nanoparticle...

Radosław Wilimski, Jan Budzianowski… in Journal of Cardiovascular Translational Re… (2024)

Article

Lipoprotein apheresis affects the concentration of extracellular vesicles in patients with elevated lipoprotein (a)

Lipoprotein apheresis (LA) is a therapeutic option for hyperlipoproteinemia(a) (hyper-Lp(a)) and atherosclerotic cardiovascular disease (ASCVD). LA improves blood rheology, reduces oxidative stress parameters ...

Joanna Marlęga-Linert, Aleksandra Gąsecka, Edwin van der Pol… in Scientific Reports (2024)

Article

Traceable characterization of hollow organosilica beads as potential reference materials for extracellular vesicle measurements with optical techniques

The concentration of cell-type specific extracellular vesicles (EVs) is a promising biomarker for various diseases. However, concentrations of EVs measured by optical techniques such as flow cytometry (FCM) or...

Jérôme Deumer, Robin Schürmann, Anikó Gaál, Zoltán Varga, Britta Bettin… in Discover Nano (2024)

Article

An imaging flow cytometry-based methodology for the analysis of single extracellular vesicles in unprocessed human plasma

Extracellular vesicles (EVs) are tissue-specific particles released by cells containing valuable diagnostic information in the form of various biomolecules. To rule out selection bias or introduction of artefa...

Wouter W. Woud, Edwin van der Pol, Erik Mul, Martin J. Hoogduijn… in Communications Biology (2022)

Article

Misinterpretation of solid sphere equivalent refractive index measurements and smallest detectable diameters of extracellular vesicles by flow cytometry

Edwin van der Pol, Ton G. van Leeuwen, **aomei Yan in Scientific Reports (2021)

Article

The generation and use of recombinant extracellular vesicles as biological reference material

Recent years have seen an increase of extracellular vesicle (EV) research geared towards biological understanding, diagnostics and therapy. However, EV data interpretation remains challenging owing to complexi...

Edward Geeurickx, Joeri Tulkens, Bert Dhondt, Jan Van Deun… in Nature Communications (2019)

Article

Precultivation of Bacillus coagulans DSM2314 in the presence of furfural decreases inhibitory effects of lignocellulosic by-products during l(+)-lactic acid fermentation

By-products resulting from thermo-chemical pretreatment of lignocellulose can inhibit fermentation of lignocellulosic sugars to lactic acid. Furfural is such a by-product, which is formed during acid pretreatm...

Edwin van der Pol, Jan Springer… in Applied Microbiology and Biotechnology (2016)

Article

Transglutaminase 2 is secreted from smooth muscle cells by transamidation-dependent microparticle formation

Transglutaminase 2 (TG2) is a pleiotropic enzyme involved in both intra- and extracellular processes. In the extracellular matrix, TG2 stabilizes the matrix by both covalent cross-linking and disulfide isomera...

Jeroen van den Akker, Angela van Weert, Gijs Afink, Erik N. T. P. Bakker… in Amino Acids (2012)