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Open AccessImmunoglobulin G N-glycan markers of accelerated biological aging during chronic HIV infection
People living with HIV (PLWH) experience increased vulnerability to premature aging and inflammation-associated comorbidities, even when HIV replication is suppressed by antiretroviral therapy (ART). However, ...
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Article
Open AccessCirculating biomarker correlates of left atrial size and myocardial extracellular volume fraction among persons living with and without HIV
Infection with human immunodeficiency virus (HIV) is associated with higher risk for myocardial disease despite modern combination antiretroviral therapy (cART). Factors contributing to this excess risk, howev...
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Article
GDF15 and Cortisol Response to Meal Tolerance Test in Post-Sleeve Gastrectomy Patients with Weight Regain
Hormonal factors behind weight regain (WR) after surgical weight loss remain inadequately understood. Growth/differentiation factor 15 (GDF15) has emerged as a potential therapeutic target in obesity treatment...
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Article
Diabetes in People with HIV
To discuss the diagnosis, treatment, and complications of diabetes in people with HIV (PWH) and to review HIV-related factors that may contribute to the development of diabetes or alter decisions in the care a...
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Article
Author Correction: HIV and antiretroviral therapy-related fat alterations
An amendment to this paper has been published and can be accessed via a link at the top of the paper.
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HIV and antiretroviral therapy-related fat alterations
Early in the HIV epidemic, lipodystrophy, characterized by subcutaneous fat loss (lipoatrophy), with or without central fat accumulation (lipohypertrophy), was recognized as a frequent condition among people l...
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Article
Limited correlation between systemic biomarkers and neurocognitive performance before and during HIV treatment
The AIDS Clinical Trials Group (ACTG) study A5303 investigated the associations between neuropsychological performance (NP) and inflammatory biomarkers in HIV-infected participants. Fifteen NP tests were admin...
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Article
Comparative Effects of Medical Versus Surgical Weight Loss on Body Composition: a Pilot Randomized Trial
Bariatric surgery leads to more rapid and greater weight loss (WL) compared to medical weight loss (MWL), but the differences in body composition (BC) changes for these modalities remain unclear. Due to the kn...
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Article
Validation of the Use of Electronic Medical Records for Identification of Post-gastric Bypass Hypoglycemia Cases
We sought to validate an algorithm designed to identify patients with post-gastric bypass hypoglycemia (PGBH) using clinician chart review.
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Article
Visceral fat is associated with brain structure independent of human immunodeficiency virus infection status
The combined effects of human immunodeficiency virus (HIV), obesity, and elevated visceral adipose tissue (VAT) on brain structure are unknown. In a cross-sectional analysis of Multicenter AIDS Cohort Study (M...
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Article
HIV and Bone Complications: Understudied Populations and New Management Strategies
The higher risk of osteoporosis and fracture associated with HIV infection and certain antiretrovirals has been well established and the need for risk stratification among older adults increasingly recognized....
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Open AccessAmerican ginseng (Panax quinquefolius) administration does not affect performance of the Roche COBAS Ampliprep/Taqman HIV-1 RNA assay
Previous data indicate that purified components of ginseng can inhibit HIV reverse transcriptase in vitro, suggesting that ginseng components in plasma may interfere with HIV-1 RNA detection assays.
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Article
Functional Impairment, Disability, and Frailty in Adults Aging with HIV-Infection
The integration of antiretroviral therapy (i.e., ART) into HIV care has dramatically extended the life expectancy of those living with HIV. However, in comparison to similar HIV-uninfected populations, HIV-inf...
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Open AccessMorning free and total testosterone in HIV-infected men: implications for the assessment of hypogonadism
Hypogonadism is common among HIV-infected men, even among men receiving antiretroviral therapy (ART). Our objective in this study was to determine the prevalence of biochemical hypogonadism among HIV-infected ...
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Article
Management of the metabolic effects of HIV and HIV drugs
Body adipose tissue changes and metabolic abnormalities are common among HIV-infected patients receiving highly active antiretroviral therapy and contribute to the risk of cardiovascular disease. This Review h...
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Open AccessFat distribution and longitudinal anthropometric changes in HIV-infected men with and without clinical evidence of lipodystrophy and HIV-uninfected controls: A substudy of the Multicenter AIDS Cohort Study
Fat abnormalities are common among HIV-infected persons, but few studies have compared regional body fat distribution, including visceral fat, in HIV-infected and HIV-uninfected persons and their subsequent tr...
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Article
Open AccessPharmacokinetic and metabolic effects of American ginseng (Panax quinquefolius) in healthy volunteers receiving the HIV protease inhibitor indinavir
Complementary and alternative medicine (CAM) use is prevalent among HIV-infected patients to reduce the toxicity of antiretroviral therapy. Ginseng has been used for treatment of hyperglycemia and insulin resi...
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Article
Fish oil supplementation in the treatment of cachexia in pancreatic cancer patients
Patients with pancreatic cancer often experience a loss of weight and appetite, known as the anorexia-cachexia syndrome, which is associated with decreased quality of life and reduced survival. Research into t...
