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  1. Article

    Open Access

    Combining Image Space and q-Space PDEs for Lossless Compression of Diffusion MR Images

    Diffusion MRI is a modern neuroimaging modality with a unique ability to acquire microstructural information by measuring water self-diffusion at the voxel level. However, it generates huge amounts of data, re...

    Ikram Jumakulyyev, Thomas Schultz in Journal of Mathematical Imaging and Vision (2023)

  2. Article

    Open Access

    Accurate drusen segmentation in optical coherence tomography via order-constrained regression of retinal layer heights

    Drusen are an important biomarker for age-related macular degeneration (AMD). Their accurate segmentation based on optical coherence tomography (OCT) is therefore relevant to the detection, staging, and treatm...

    Olivier Morelle, Maximilian W. M. Wintergerst, Robert P. Finger in Scientific Reports (2023)

  3. No Access

    Article

    Molecular-beam spectroscopy with an infinite interferometer: spectroscopic resolution and accuracy

    An interferometer with effectively infinite maximum optical path difference removes the dominant resolution limit for interferometric spectroscopy. We present mass-correlated rotational Raman spectra that repr...

    Thomas Schultz, In Heo, Jong Chan Lee in Journal of the Korean Physical Society (2023)

  4. No Access

    Chapter and Conference Paper

    Segmentation Distortion: Quantifying Segmentation Uncertainty Under Domain Shift via the Effects of Anomalous Activations

    Domain shift occurs when training U-Nets for medical image segmentation with images from one device, but applying them to images from a different device. This often reduces accuracy, and it poses a challenge f...

    Jonathan Lennartz, Thomas Schultz in Medical Image Computing and Computer Assis… (2023)

  5. No Access

    Chapter and Conference Paper

    Anisotropic Fanning Aware Low-Rank Tensor Approximation Based Tractography

    Low-rank higher-order tensor approximation has been used successfully to extract discrete directions for tractography from continuous fiber orientation density functions (fODFs). However, while it accounts for...

    Johannes Gruen, Jonah Sieg, Thomas Schultz in Computational Diffusion MRI (2023)

  6. No Access

    Article

    Reducing instability of inter-subject covariance of FDG uptake networks using structure-weighted sparse estimation approach

    Sparse inverse covariance estimation (SICE) is increasingly utilized to estimate inter-subject covariance of FDG uptake (FDGcov) as proxy of metabolic brain connectivity. However, this statistical method suffers ...

    Min Wang, Michael Schutte, Timo Grimmer in European Journal of Nuclear Medicine and M… (2022)

  7. Article

    Open Access

    Erfahrungen mit der digitalen Versorgung von Patienten mit chronischen und akuten Lungenerkrankungen während der SARS-CoV-2-Pandemie

    Das Management von Patienten mit respiratorischen Erkrankungen ist seit Beginn der Severe-acute-respiratory-syndrome-coronavirus-2(SARS-CoV-2)-Pandemie durch Maßnahmen zur Infektionsprävention teilweise erschw...

    Marcel Braun, Olaf Schmidt, Thomas Schultz, Holger Woehrle in Der Internist (2022)

  8. No Access

    Article

    Smartphone-basierte Fundusfotografie: Anwendungen und Adapter

    Die Smartphone-basierte Fundusfotografie (SBF) stellt eine innovative und kostengünstige Möglichkeit zur Bildgebung des Augenhintergrundes dar. Seit den ersten Anwendungsberichten von vor über 10 Jahren wurde ...

    Linus G. Jansen, Thomas Schultz, Frank G. Holz, Robert P. Finger in Der Ophthalmologe (2022)

  9. Article

    Open Access

    Multiple instance learning detects peripheral arterial disease from high-resolution color fundus photography

    Peripheral arterial disease (PAD) is caused by atherosclerosis and is a common disease of the elderly leading to excess morbidity and mortality. Early PAD diagnosis is important, as the only available causal t...

    Simon Mueller, Maximilian W. M. Wintergerst, Peyman Falahat in Scientific Reports (2022)

  10. No Access

    Chapter and Conference Paper

    Adaptive Optimization with Fewer Epochs Improves Across-Scanner Generalization of U-Net Based Medical Image Segmentation

    The U-Net architecture is widely used for medical image segmentation. However, accuracy has been observed to drop, sometimes dramatically, when U-Nets are trained on images that have been acquired with a speci...

    Rasha Sheikh, Morris Klasen in Domain Adaptation and Representation Transfer (2022)

  11. No Access

    Chapter

    Life Cycles of International Law as a Noetic Unity: The Various Times of Law-Thinking

    Different possible temporalities, or life cycles, structure international lawmaking if international law is taken as a noetic unity—a complex whole that is created by an exercise of reason and that does not ex...

    Thomas Schultz in International Law and Time (2022)

  12. Article

    Open Access

    T2-Pseudonormalization and Microstructural Characterization in Advanced Stages of Late-infantile Metachromatic Leukodystrophy

    T2-weighted signal hyperintensities in white matter (WM) are a diagnostic finding in brain magnetic resonance imaging (MRI) of patients with metachromatic leukodystrophy (MLD). In our systematic investigation ...

    Pascal Martin, Gisela E. Hagberg, Thomas Schultz, Klaus Harzer in Clinical Neuroradiology (2021)

  13. Article

    Open Access

    Author Correction: Replication and Refinement of an Algorithm for Automated Drusen Segmentation on Optical Coherence Tomography

    Maximilian W. M. Wintergerst, Shekoufeh Gorgi Zadeh, Vitalis Wiens in Scientific Reports (2021)

  14. No Access

    Chapter and Conference Paper

    Predicting Treatment Response in Prostate Cancer Patients Based on Multimodal PET/CT for Clinical Decision Support

    Clinical decision support systems (CDSSs) have gained critical importance in clinical practice and research. Machine learning (ML) and deep learning methods are widely applied in CDSSs to provide diagnostic an...

    Sobhan Moazemi, Markus Essler in Multimodal Learning for Clinical Decision … (2021)

  15. No Access

    Chapter and Conference Paper

    Lossless PDE-based Compression of 3D Medical Images

    Inpainting with Partial Differential Equations (PDEs) has previously been used as a basis for lossy image compression. For medical images, lossless compression is often considered to be safer, given that even ...

    Ikram Jumakulyyev, Thomas Schultz in Scale Space and Variational Methods in Computer Vision (2021)

  16. Chapter and Conference Paper

    Fourth-Order Anisotropic Diffusion for Inpainting and Image Compression

    Edge-enhancing diffusion (EED) can reconstruct a close approximation of an original image from a small subset of its pixels. This makes it an attractive foundation for PDE based image compression. In this work...

    Ikram Jumakulyyev, Thomas Schultz in Anisotropy Across Fields and Scales (2021)

  17. No Access

    Chapter

    Empirically Map** Investment Arbitration Scholarship: Networks, Authorities, and the Research Front

    Scholarship on international investment arbitration is plentiful. Despite it being a relatively young field, it would be difficult to name one in which more books and articles have been published in recent yea...

    Niccolò Ridi, Thomas Schultz in Private Actors in International Investment Law (2021)

  18. Article

    Open Access

    Replication and Refinement of an Algorithm for Automated Drusen Segmentation on Optical Coherence Tomography

    Here, we investigate the extent to which re-implementing a previously published algorithm for OCT-based drusen quantification permits replicating the reported accuracy on an independent dataset. We refined tha...

    Maximilian W. M. Wintergerst, Shekoufeh Gorgi Zadeh, Vitalis Wiens in Scientific Reports (2020)

  19. No Access

    Chapter and Conference Paper

    Automated Detection of Diabetic Retinopathy from Smartphone Fundus Videos

    Even though it is important to screen patients with diabetes for signs of diabetic retinopathy (DR), doing so comprehensively remains a practical challenge in low- and middle-income countries due to limited re...

    Simon Mueller, Snezhana Karpova in Ophthalmic Medical Image Analysis (2020)

  20. No Access

    Chapter and Conference Paper

    Feature Preserving Smoothing Provides Simple and Effective Data Augmentation for Medical Image Segmentation

    CNNs represent the current state of the art for image classification, as well as for image segmentation. Recent work suggests that CNNs for image classification suffer from a bias towards texture, and that red...

    Rasha Sheikh, Thomas Schultz in Medical Image Computing and Computer Assis… (2020)

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