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  1. Article

    Open Access

    Management of type 2 diabetes with the dual GIP/GLP-1 receptor agonist tirzepatide: a systematic review and meta-analysis

    Tirzepatide is a novel dual glucose-dependent insulinotropic peptide (GIP) and glucagon-like peptide-1 receptor agonist (GLP-1 RA) currently under review for marketing approval. Individual trials have assessed...

    Thomas Karagiannis, Ioannis Avgerinos, Aris Liakos, Stefano Del Prato in Diabetologia (2022)

  2. Article

    Open Access

    Socioeconomic aspects of incretin-based therapy

    Incretin-based therapies, particularly glucagon-like peptide-1 receptor agonists (GLP-1 RAs), have demonstrated cardiovascular benefits in people with type 2 diabetes. However, socioeconomic disparities in the...

    Thomas Karagiannis, Eleni Bekiari, Apostolos Tsapas in Diabetologia (2023)

  3. Article

    Open Access

    Subcutaneously administered tirzepatide vs semaglutide for adults with type 2 diabetes: a systematic review and network meta-analysis of randomised controlled trials

    We conducted a systematic review and network meta-analysis to compare the efficacy and safety of s.c. administered tirzepatide vs s.c. administered semaglutide for adults of both sexes with type 2 diabetes mel...

    Thomas Karagiannis, Konstantinos Malandris, Ioannis Avgerinos in Diabetologia (2024)