10 Result(s)

Article

Cross-species comparative analysis of single presynapses

Comparing brain structure across species and regions enables key functional insights. Leveraging publicly available data from a novel mass cytometry-based method, synaptometry by time of flight (SynTOF), we ap...

Eloïse Berson, Chandresh R. Gajera, Thanaphong Phongpreecha… in Scientific Reports (2023)

Article

Correction to: Temporal emergence of age-associated changes in cognitive and physical function in vervets (Chlorocebus aethiops sabaeus)

Brett M. Frye, Payton M. Valure, Suzanne Craft, Mark G. Baxter… in GeroScience (2021)

Article

Diet, obesity, and the gut microbiome as determinants modulating metabolic outcomes in a non-human primate model

The objective of this study was to increase understanding of the complex interactions between diet, obesity, and the gut microbiome of adult female non-human primates (NHPs). Subjects consumed either a Western (n

Tiffany M. Newman, Carol A. Shively, Thomas C. Register, Susan E. Appt… in Microbiome (2021)

Article

Genome-wide association study of coronary artery calcified atherosclerotic plaque in African Americans with type 2 diabetes

Coronary artery calcified atherosclerotic plaque (CAC) predicts cardiovascular disease (CVD). Despite exposure to more severe conventional CVD risk factors, African Americans (AAs) are less likely to develop C...

Jasmin Divers, Nicholette D. Palmer, Carl D. Langefeld, W. Mark Brown… in BMC Genetics (2017)

Article

In vivo transplantation of 3D encapsulated ovarian constructs in rats corrects abnormalities of ovarian failure

Safe clinical hormone replacement (HR) will likely become increasingly important in the growing populations of aged women and cancer patients undergoing treatments that ablate the ovaries. Cell-based HRT (cHRT...

Sivanandane Sittadjody, Justin M. Saul, John P. McQuilling… in Nature Communications (2017)

Article

Transcriptomic profiles of aging in purified human immune cells

Transcriptomic studies hold great potential towards understanding the human aging process. Previous transcriptomic studies have identified many genes with age-associated expression levels; however, small sampl...

Lindsay M Reynolds, **gzhong Ding, Jackson R Taylor, Kurt Lohman… in BMC Genomics (2015)

Article

Progestin effects on cell proliferation pathways in the postmenopausal mammary gland

Menopausal hormone therapies vary widely in their effects on breast cancer risk, and the mechanisms underlying these differences are unclear. The primary goals of this study were to characterize the mammary gl...

Charles E Wood, Daniel Branstetter, Allison P Jacob, J Mark Cline… in Breast Cancer Research (2013)

Article

Relationships between serum MCP-1 and subclinical kidney disease: African American-Diabetes Heart Study

Monocyte chemoattractant protein-1 (MCP-1) plays important roles in kidney disease susceptibility and atherogenesis in experimental models. Relationships between serum MCP-1 concentration and early nephropathy...

Mariana Murea, Thomas C Register, Jasmin Divers, Donald W Bowden… in BMC Nephrology (2012)

Article

Abdominal aortic calcification quantified by the Morphological Atherosclerotic Calcification Distribution (MACD) index is associated with features of the metabolic syndrome

Abdominal aortic calcifications (AAC) predict cardiovascular mortality. A new scoring model for AAC, the Morphological Atherosclerotic Calcification Distribution (MACD) index may contribute with additional inf...

Natasha Barascuk, Melanie Ganz, Mads Nielsen… in BMC Cardiovascular Disorders (2011)

Article

Human macrophage foam cells degrade atherosclerotic plaques through cathepsin K mediated processes

Proteolytic degradation of Type I Collagen by proteases may play an important role in remodeling of atherosclerotic plaques, contributing to increased risk of plaque rupture.

Natasha Barascuk, Helene Skjøt-Arkil, Thomas C Register… in BMC Cardiovascular Disorders (2010)