-
Article
Open AccessPersistent symptoms after COVID-19 are not associated with differential SARS-CoV-2 antibody or T cell immunity
Among the unknowns in decoding the pathogenesis of SARS-CoV-2 persistent symptoms in Long Covid is whether there is a contributory role of abnormal immunity during acute infection. It has been proposed that Lo...
-
Article
Open AccessModel-free phasor image analysis of quantitative myocardial T1 map**
Model-free phasor image analysis, well established in fluorescence lifetime imaging and only recently applied to qMRI \({T}_{2}\) ...
-
Article
Open AccessPrecision measurement of cardiac structure and function in cardiovascular magnetic resonance using machine learning
Measurement of cardiac structure and function from images (e.g. volumes, mass and derived parameters such as left ventricular (LV) ejection fraction [LVEF]) guides care for millions. This is best assessed usin...
-
Article
Open AccessPre-existing polymerase-specific T cells expand in abortive seronegative SARS-CoV-2
Individuals with potential exposure to severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) do not necessarily develop PCR or antibody positivity, suggesting that some individuals may clear subclinical...
-
Article
Open AccessMyocardial changes on 3T cardiovascular magnetic resonance imaging in response to haemodialysis with fluid removal
Map** of left ventricular (LV) native T1 is a promising non-invasive, non-contrast imaging biomarker. Native myocardial T1 times are prolonged in patients requiring dialysis, but there are concerns that the ...
-
Article
Open AccessUse of quantitative cardiovascular magnetic resonance myocardial perfusion map** for characterization of ischemia in patients with left internal mammary coronary artery bypass grafts
Quantitative myocardial perfusion map** using cardiovascular magnetic resonance (CMR) is validated for myocardial blood flow (MBF) estimation in native vessel coronary artery disease (CAD). Following coronar...
-
Article
Open AccessMyocardial fibrosis in asymptomatic and symptomatic chronic severe primary mitral regurgitation and relationship to tissue characterisation and left ventricular function on cardiovascular magnetic resonance
Myocardial fibrosis occurs in end-stage heart failure secondary to mitral regurgitation (MR), but it is not known whether this is present before onset of symptoms or myocardial dysfunction. This study aimed to...
-
Article
Open AccessH3K27ac acetylome signatures reveal the epigenomic reorganization in remodeled non-failing human hearts
H3K27ac histone acetylome changes contribute to the phenotypic response in heart diseases, particularly in end-stage heart failure. However, such epigenetic alterations have not been systematically investigate...
-
Article
Open AccessValidation of four-dimensional flow cardiovascular magnetic resonance for aortic stenosis assessment
The management of patients with aortic stenosis (AS) crucially depends on accurate diagnosis. The main aim of this study were to validate the four-dimensional flow (4D flow) cardiovascular magnetic resonance (...
-
Article
Open AccessRelationship between endotoxin core, staphylococcal and varicella antibody levels and outcome following aortic valve replacement surgery: a prospective observational study
Morbidity and mortality following cardiac valve surgery is high. Immunity is an important contributor to outcome. This study examines the relationship of staphylococcal and endotoxin antibody levels to outcome...
-
Article
Open AccessMyocardial Extracellular Volume Quantification by Cardiovascular Magnetic Resonance and Computed Tomography
This review article discusses the evolution of extracellular volume (ECV) quantification using both cardiovascular magnetic resonance (CMR) and computed tomography (CT).
-
Article
Open AccessRedefining viability by cardiovascular magnetic resonance in acute ST-segment elevation myocardial infarction
In chronic myocardial infarction (MI), segments with a transmural extent of infarct (TEI) of ≤50% are defined as being viable. However, in the acute phase of an ST-segment elevation myocardial infarction (STEM...
-
Article
Open AccessDefining left ventricular remodeling following acute ST-segment elevation myocardial infarction using cardiovascular magnetic resonance
The assessment of post-myocardial infarction (MI) left ventricular (LV) remodeling by cardiovascular magnetic resonance (CMR) currently uses criteria defined by echocardiography. Our aim was to provide CMR cri...
-
Article
Open AccessA case report in cardiovascular magnetic resonance: the contrast agent matters in amyloid
Cardiac amyloidosis is a progressive but underdiagnosed and underappreciated cause of heart failure. In the last few years, cardiovascular magnetic resonance (CMR) has become the gold standard for non invasive...
-
Article
Open AccessAortic Stenosis, a Left Ventricular Disease: Insights from Advanced Imaging
Aortic stenosis (AS) is the most common primary valve disorder in the elderly with an increasing prevalence. It is increasingly clear that it is also a disease of the left ventricle (LV) rather than purely the...
-
Article
Open AccessReproducibility of native T1 map** using ShMOLLI and MOLLI - implications for sample size calculation
-
Article
Open AccessChronic iron deposit and left ventricular remodeling in reperfused STEMI patients
-
Article
Open AccessDiffuse myocardial fibrosis - a therapeutic target? Proof of regression at 1-year following aortic valve replacement: the RELIEF-AS study
-
Article
Open AccessHematocrit, iron and HDL-cholesterol explain 90% of variation in native blood T1
-
Article
Open AccessLeft ventricular remodeling after reperfused acute myocardial infarction: insights from automated ECV map**
