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  1. Article

    Open Access

    Evidence map** on how to perform an optimal surgical repair of large hiatal hernias

    Symptomatic and large hiatal hernia (HH) is a common disorder requiring surgical management. However, there is a lack of systematic, evidence-based recommendations summarizing recent reviews on surgical treatm...

    Felix Nickel, Philip C. Müller, Amila Cizmic in Langenbeck's Archives of Surgery (2023)

  2. Article

    Open Access

    Lymphoepithelial cyst of the pancreas: can common imaging features help to avoid resection?

    Differentiation of cystic pancreatic neoplasms remains a challenging task for radiologists regarding the main aim of identifying malignant and premalignant lesions.

    Ekaterina Khristenko, Elena Esteban Garcia in Langenbeck's Archives of Surgery (2023)

  3. Article

    Open Access

    State-of-the-art surgery for pancreatic cancer

    The d evelopment of surgical techniques and specialization and specifically complication management in pancreatic surgery have improved surgical outcomes as well as oncological results in pancreatic surgery in...

    Anna Nießen, Thilo Hackert in Langenbeck's Archives of Surgery (2022)

  4. No Access

    Article

    Technical progress in robotic pancreatoduodenectomy: TRIANGLE and periadventitial dissection for retropancreatic nerve plexus resection

    The resection of retropancreatic nerve plexuses for pancreatic head cancer became standard of care during open pancreatoduodenectomy to minimize local recurrences. Since more surgical centers are progressing o...

    Benedict Kinny-Köster, Joseph R. Habib, Ammar A. Javed in Langenbeck's Archives of Surgery (2021)

  5. Article

    Open Access

    Splenorenal shunt for reconstruction of the gastric and splenic venous drainage during pancreatoduodenectomy with resection of the portal venous confluence

    Resection of the portal venous confluence is frequently necessary for radical resection during pancreatoduodenectomy for cancer. However, ligation of the splenic vein can cause serious postoperative complicati...

    Mohammed Al-Saeedi, Leonie Frank-Moldzio, Pietro Contin in Langenbeck's Archives of Surgery (2021)

  6. Article

    Open Access

    Severe acute pancreatitis: surgical indications and treatment

    Acute pancreatitis (AP) is defined as an acute inflammatory attack of the pancreas of sudden onset. Around 25% of patients have either moderately severe or severe disease with a mortality rate of 15–20%.

    Max Heckler, Thilo Hackert, Kai Hu in Langenbeck's Archives of Surgery (2021)

  7. Article

    Open Access

    Meta-analysis of primary open versus closed cannulation strategy for totally implantable venous access port implantation

    There is still no reference standard for the implantation of totally implantable venous access ports (TIVAPs). A recently published multicentre randomised controlled trial (RCT) revealed a significantly greate...

    Ulla Klaiber, Pascal Probst, Matthes Hackbusch in Langenbeck's Archives of Surgery (2021)

  8. Article

    Open Access

    Cavernous transformation of the portal vein in pancreatic cancer surgery—venous bypass graft first

    In recent years, several techniques have been introduced to allow safe oncologic resections of cancers of the pancreatic head. While resections of the mesenterico-portal axis became now a part of the routine t...

    Thomas Schmidt, Oliver Strobel, Martin Schneider in Langenbeck's Archives of Surgery (2020)

  9. No Access

    Article

    Pancreatic resection for cancer—the Heidelberg technique

    Pancreatic cancer is associated with high recurrence rates, and any surgery should aim to prevent local recurrence. However, systematic resection of putatively tumor-infiltrated soft tissue adjacent to the cel...

    Martin Schneider, Oliver Strobel, Thilo Hackert in Langenbeck's Archives of Surgery (2019)

  10. No Access

    Article

    Pancreatic surgery: we need clear definitions

    Pancreatic surgery has undergone substantial changes during the last decades. Improved surgical techniques and perioperative care have contributed to improved outcomes and allow safe surgery with mortality rat...

    André Mihaljevic, Mohammed Al-Saeedi, Thilo Hackert in Langenbeck's Archives of Surgery (2019)

  11. No Access

    Article

    Neoadjuvant and adjuvant chemotherapy in pancreatic cancer

    Only 15–20% of patients with pancreatic ductal adenocarcinoma (PDAC) have a resectable tumor at the time of diagnosis. Effective multimodal treatment concepts including neoadjuvant chemotherapy are therefore n...

    Ulla Klaiber, Carl-Stephan Leonhardt, Oliver Strobel in Langenbeck's Archives of Surgery (2018)

  12. No Access

    Article

    Postoperative outcome and quality of life after surgery for FAP-associated duodenal adenomatosis

    Prophylactic colon surgery has increased life expectancy of familial adenomatous polyposis patients. Extracolonic manifestations are life limiting, above all duodenal adenomas. Severe duodenal adenomatosis or ...

    Petra Ganschow, Thilo Hackert, Marcel Biegler in Langenbeck's Archives of Surgery (2018)

  13. No Access

    Article

    Successful ablation of lymph nodes using irreversible electroporation (IRE) in a porcine survival model

    Irreversible electroporation (IRE), a nonthermal injury ablation technique, has been shown to be effective and safe in various organs, such as in the kidney, liver, prostate, or in pancreas. In contrast to rad...

    Stefan Fritz, Christof M. Sommer, Thomas Longerich in Langenbeck's Archives of Surgery (2017)

  14. No Access

    Article

    Effectiveness of Tachosil® in the prevention of postoperative pancreatic fistula after distal pancreatectomy: a systematic review and meta-analysis

    Postoperative pancreatic fistula (POPF) is a frequent and clinically relevant problem after distal pancreatectomy. A variety of methods have been tested in the attempt to prevent POPF, most of them without con...

    Felix J. Hüttner, André L. Mihaljevic, Thilo Hackert in Langenbeck's Archives of Surgery (2016)

  15. No Access

    Article

    Isolation and culture of primary human pancreatic stellate cells that reflect the context of their tissue of origin

    Pancreatic stellate cells (PSCs) play a critical role in pancreatic ductal adenocarcinoma (PDAC). Activated PSCs are the main source of fibrosis in chronic pancreatitis and of desmoplasia in PDAC. The majority...

    Oliver Strobel, Nigora Dadabaeva, Klaus Felix in Langenbeck's Archives of Surgery (2016)

  16. No Access

    Article

    Emergency pancreatic surgery—demanding and dangerous

    Elective pancreatic surgery can be carried out with mortality rates below 5 % in specialized centers today. Only few data exist on pancreatic resections in emergency situations. The aim of the study was to cha...

    Oliver Strobel, Lutz Schneider, Sebastian Philipp in Langenbeck's Archives of Surgery (2015)

  17. No Access

    Article

    Palliative resection of the primary tumor in 442 metastasized neuroendocrine tumors of the pancreas: a population-based, propensity score-matched survival analysis

    There is an ongoing debate on whether palliative removal of the primary tumor may result in a survival benefit for patients with incurable stage IV pancreatic neuroendocrine tumors (P-NET). The objective of th...

    Felix J. Hüttner, Lutz Schneider, Ignazio Tarantino in Langenbeck's Archives of Surgery (2015)

  18. No Access

    Article

    Splenic artery use for arterial reconstruction in pancreatic surgery

    Extended resections in the upper GI tract, especially for pancreatic malignancies, can require resection of the hepatic or superior mesenteric artery. Besides venous or allogenous grafting, the splenic artery ...

    Thilo Hackert, Jürgen Weitz, Markus W. Büchler in Langenbeck's Archives of Surgery (2014)

  19. No Access

    Article

    Distal pouch reconstruction with transverse jejunoplasty after experimental gastrectomy

    Various reconstruction methods with or without reservoir formation after total gastrectomy have been established. Transverse intestinoplasty has benefits as a functional peristalsis modification in rectal rese...

    Thilo Hackert, Dmitriy I. Dovzhanskiy, Stefan Tudor in Langenbeck's Archives of Surgery (2012)

  20. No Access

    Article

    Enucleation in pancreatic surgery: indications, technique, and outcome compared to standard pancreatic resections

    Pancreatic surgery is a technically challenging intervention with high demands for preoperative diagnostics and perioperative management. A perioperative mortality rate below 5% is achieved in high-volume cent...

    Thilo Hackert, Ulf Hinz, Stefan Fritz, Oliver Strobel in Langenbeck's Archives of Surgery (2011)

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