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Article
Open AccessEvidence map** on how to perform an optimal surgical repair of large hiatal hernias
Symptomatic and large hiatal hernia (HH) is a common disorder requiring surgical management. However, there is a lack of systematic, evidence-based recommendations summarizing recent reviews on surgical treatm...
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Article
Open AccessLymphoepithelial cyst of the pancreas: can common imaging features help to avoid resection?
Differentiation of cystic pancreatic neoplasms remains a challenging task for radiologists regarding the main aim of identifying malignant and premalignant lesions.
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Article
Open AccessState-of-the-art surgery for pancreatic cancer
The d evelopment of surgical techniques and specialization and specifically complication management in pancreatic surgery have improved surgical outcomes as well as oncological results in pancreatic surgery in...
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Article
Technical progress in robotic pancreatoduodenectomy: TRIANGLE and periadventitial dissection for retropancreatic nerve plexus resection
The resection of retropancreatic nerve plexuses for pancreatic head cancer became standard of care during open pancreatoduodenectomy to minimize local recurrences. Since more surgical centers are progressing o...
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Article
Open AccessSplenorenal shunt for reconstruction of the gastric and splenic venous drainage during pancreatoduodenectomy with resection of the portal venous confluence
Resection of the portal venous confluence is frequently necessary for radical resection during pancreatoduodenectomy for cancer. However, ligation of the splenic vein can cause serious postoperative complicati...
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Article
Open AccessSevere acute pancreatitis: surgical indications and treatment
Acute pancreatitis (AP) is defined as an acute inflammatory attack of the pancreas of sudden onset. Around 25% of patients have either moderately severe or severe disease with a mortality rate of 15–20%.
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Article
Open AccessMeta-analysis of primary open versus closed cannulation strategy for totally implantable venous access port implantation
There is still no reference standard for the implantation of totally implantable venous access ports (TIVAPs). A recently published multicentre randomised controlled trial (RCT) revealed a significantly greate...
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Article
Open AccessCavernous transformation of the portal vein in pancreatic cancer surgery—venous bypass graft first
In recent years, several techniques have been introduced to allow safe oncologic resections of cancers of the pancreatic head. While resections of the mesenterico-portal axis became now a part of the routine t...
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Article
Pancreatic resection for cancer—the Heidelberg technique
Pancreatic cancer is associated with high recurrence rates, and any surgery should aim to prevent local recurrence. However, systematic resection of putatively tumor-infiltrated soft tissue adjacent to the cel...
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Article
Pancreatic surgery: we need clear definitions
Pancreatic surgery has undergone substantial changes during the last decades. Improved surgical techniques and perioperative care have contributed to improved outcomes and allow safe surgery with mortality rat...
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Article
Neoadjuvant and adjuvant chemotherapy in pancreatic cancer
Only 15–20% of patients with pancreatic ductal adenocarcinoma (PDAC) have a resectable tumor at the time of diagnosis. Effective multimodal treatment concepts including neoadjuvant chemotherapy are therefore n...
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Article
Postoperative outcome and quality of life after surgery for FAP-associated duodenal adenomatosis
Prophylactic colon surgery has increased life expectancy of familial adenomatous polyposis patients. Extracolonic manifestations are life limiting, above all duodenal adenomas. Severe duodenal adenomatosis or ...
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Article
Successful ablation of lymph nodes using irreversible electroporation (IRE) in a porcine survival model
Irreversible electroporation (IRE), a nonthermal injury ablation technique, has been shown to be effective and safe in various organs, such as in the kidney, liver, prostate, or in pancreas. In contrast to rad...
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Article
Effectiveness of Tachosil® in the prevention of postoperative pancreatic fistula after distal pancreatectomy: a systematic review and meta-analysis
Postoperative pancreatic fistula (POPF) is a frequent and clinically relevant problem after distal pancreatectomy. A variety of methods have been tested in the attempt to prevent POPF, most of them without con...
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Article
Isolation and culture of primary human pancreatic stellate cells that reflect the context of their tissue of origin
Pancreatic stellate cells (PSCs) play a critical role in pancreatic ductal adenocarcinoma (PDAC). Activated PSCs are the main source of fibrosis in chronic pancreatitis and of desmoplasia in PDAC. The majority...
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Article
Emergency pancreatic surgery—demanding and dangerous
Elective pancreatic surgery can be carried out with mortality rates below 5 % in specialized centers today. Only few data exist on pancreatic resections in emergency situations. The aim of the study was to cha...
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Article
Palliative resection of the primary tumor in 442 metastasized neuroendocrine tumors of the pancreas: a population-based, propensity score-matched survival analysis
There is an ongoing debate on whether palliative removal of the primary tumor may result in a survival benefit for patients with incurable stage IV pancreatic neuroendocrine tumors (P-NET). The objective of th...
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Article
Splenic artery use for arterial reconstruction in pancreatic surgery
Extended resections in the upper GI tract, especially for pancreatic malignancies, can require resection of the hepatic or superior mesenteric artery. Besides venous or allogenous grafting, the splenic artery ...
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Article
Distal pouch reconstruction with transverse jejunoplasty after experimental gastrectomy
Various reconstruction methods with or without reservoir formation after total gastrectomy have been established. Transverse intestinoplasty has benefits as a functional peristalsis modification in rectal rese...
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Article
Enucleation in pancreatic surgery: indications, technique, and outcome compared to standard pancreatic resections
Pancreatic surgery is a technically challenging intervention with high demands for preoperative diagnostics and perioperative management. A perioperative mortality rate below 5% is achieved in high-volume cent...