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  1. Article

    Open Access

    Intraoperative strategies and techniques to achieve surgical radicality in pancreatic cancer

    The treatment of pancreatic cancer presents a challenging task in surgical oncology, demanding innovative approaches to achieve radical resection and improve patient outcomes. This article provides an overview...

    Thomas Hank, Carl-Stephan Leonhardt, Ulla Klaiber, Oliver Strobel MD in European Surgery (2024)

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  2. Article

    Open Access

    Single-cell analysis of patient-derived PDAC organoids reveals cell state heterogeneity and a conserved developmental hierarchy

    Pancreatic ductal adenocarcinoma (PDAC) is projected to be the second leading cause of cancer mortality by 2030. Bulk transcriptomic analyses have distinguished ‘classical’ from ‘basal-like’ tumors with more a...

    Teresa G. Krieger, Solange Le Blanc, Julia Jabs, Foo Wei Ten… in Nature Communications (2021)

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  3. No Access

    Article

    Neoadjuvant and adjuvant chemotherapy in pancreatic cancer

    Only 15–20% of patients with pancreatic ductal adenocarcinoma (PDAC) have a resectable tumor at the time of diagnosis. Effective multimodal treatment concepts including neoadjuvant chemotherapy are therefore n...

    Ulla Klaiber, Carl-Stephan Leonhardt, Oliver Strobel… in Langenbeck's Archives of Surgery (2018)