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Article
Open AccessA dopaminergic mechanism of antipsychotic drug efficacy, failure, and failure reversal: the role of the dopamine transporter
Antipsychotic drugs are effective interventions in schizophrenia. However, the efficacy of these agents often decreases over time, which leads to treatment failure and symptom recurrence. We report that antips...
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Article
Open AccessOff-label prescription of psychiatric drugs by non-psychiatrist physicians in three general hospitals in Germany
Off-label prescribing of psychoactive drugs is a common practice in psychiatry. Here, we sought to investigate the frequency of off-label prescribing in a population of hospitalized patients with a somatic ill...
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Article
Open AccessDas AMDS-System zur Dokumentation von Schmerzbefunden
Die Autoren stellen als Arbeitsgemeinschaft für Methodik und Dokumentation von Schmerzbefunden (AMDS) ein System zur Befunderhebung vor. Dieses lehnt sich in seiner Struktur an das AMDP-System (System der Arbe...
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Article
Open AccessVisualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level
G protein–coupled receptors (GPCRs), including dopamine receptors, represent a group of important pharmacological targets. An increased formation of dopamine receptor D2 homodimers has been suggested to be associ...