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Article
Open AccessFluorescent ligands for dopamine D2/D3 receptors
Fluorescent ligands are versatile tools for the study of G protein-coupled receptors. Depending on the fluorophore, they can be used for a range of different applications, including fluorescence microscopy and...
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Article
Open AccessVisualization of ligand-induced dopamine D2S and D2L receptor internalization by TIRF microscopy
G protein-coupled receptors (GPCRs), including the dopamine receptors, represent a group of important pharmacological targets. Upon agonist binding, GPCRs frequently undergo internalization, a process that is ...
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Article
Open AccessVisualization and ligand-induced modulation of dopamine receptor dimerization at the single molecule level
G protein–coupled receptors (GPCRs), including dopamine receptors, represent a group of important pharmacological targets. An increased formation of dopamine receptor D2 homodimers has been suggested to be associ...
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Article
The pH Probe CypHer™5E is Effectively Quenched by FM Dyes
Concurrent imaging of spectrally distinct fluorescence probes has become an important method for live-cell microscopy experiments in many biological disciplines. The technique enables the identification of a m...