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Article
ER and PR signaling nodes during mammary gland development
The ovarian hormones estrogen and progesterone orchestrate postnatal mammary gland development and are implicated in breast cancer. Most of our understanding of the molecular mechanisms of estrogen receptor (E...
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Article
High hopes for RANKL: will the mouse model live up to its promise?
The steroid hormones, estrogens and progesterone are key drivers of postnatal breast development and are linked to breast carcinogenesis. Experiments in the mouse mammary gland have revealed that they rely on ...
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Article
Concerted regulation of nuclear and cytoplasmic activities of SR proteins by AKT
Serine/arginine-rich (SR) proteins are important regulators of mRNA splicing. Several postsplicing activities have been described for a subset of shuttling SR proteins, including regulation of mRNA export and ...
