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    Article

    Chloroplast-actin filaments decide the direction of chloroplast avoidance movement under strong light in Arabidopsis thaliana

    Chloroplast-actin (cp-actin) filaments are crucial for light-induced chloroplast movement, and appear in the front region of moving chloroplasts when visualized using GFP-mouse Talin. They are short and thick,...

    Masamitsu Wada, Takeshi Higa, Kaoru Katoh, Nobuko Moritoki in Journal of Plant Research (2024)

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    Article

    Microtubule-associated phase separation of MIDD1 tunes cell wall spacing in xylem vessels in Arabidopsis thaliana

    Properly patterned cell walls specify cellular functions in plants. Differentiating protoxylem and metaxylem vessel cells exhibit thick secondary cell walls in striped and pitted patterns, respectively. Cortic...

    Takeshi Higa, Saku T. Kijima, Takema Sasaki, Shogo Takatani, Ryosuke Asano in Nature Plants (2024)

  3. Article

    Open Access

    A fungal sesquiterpene biosynthesis gene cluster critical for mutualist-pathogen transition in Colletotrichum tofieldiae

    Plant-associated fungi show diverse lifestyles from pathogenic to mutualistic to the host; however, the principles and mechanisms through which they shift the lifestyles require elucidation. The root fungus Colle...

    Kei Hiruma, Seishiro Aoki, Junya Takino, Takeshi Higa in Nature Communications (2023)

  4. Article

    Paraneoplastic Myasthenia Gravis Due to Ovarian Cancer

    Tomonori Kurimoto, Tsuyoshi Matsuoka, Takehiro Matsuda in Indian Journal of Pediatrics (2023)

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    Article

    Light-induced chloroplast movements in Oryza species

    Light-induced chloroplast movements control efficient light utilization in leaves, and thus, are essential for leaf photosynthesis and biomass production under fluctuating light conditions. Chloroplast movemen...

    Miki Kihara, Tomokazu Ushijima, Yoshiyuki Yamagata in Journal of Plant Research (2020)

  6. Article

    Open Access

    Palisade cell shape affects the light-induced chloroplast movements and leaf photosynthesis

    Leaf photosynthesis is regulated by multiple factors that help the plant to adapt to fluctuating light conditions. Leaves of sun-light-grown plants are thicker and contain more columnar palisade cells than tho...

    Eiji Gotoh, Noriyuki Suetsugu, Takeshi Higa, Tomonao Matsushita in Scientific Reports (2018)

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    Article

    Prophylactic use of octreotide for asparaginase-induced acute pancreatitis

    In the present study, we sought to evaluate the prophylactic use of octreotide for asparaginase-induced acute pancreatitis. We reviewed the medical records of seven patients in two institutions who received pr...

    Sachi Sakaguchi, Takeshi Higa, Mitsuyoshi Suzuki in International Journal of Hematology (2017)

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    Article

    Temperature-dependent signal transmission in chloroplast accumulation response

    Chloroplast photorelocation movement, well-characterized light-induced response found in various plant species from alga to higher plants, is an important phenomenon for plants to increase photosynthesis effic...

    Takeshi Higa, Satoshi Hasegawa, Yoshio Hayasaki, Yutaka Kodama in Journal of Plant Research (2017)

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    Article

    Functional characterization of blue-light-induced responses and PHOTOTROPIN 1 gene in Welwitschia mirabilis

    The blue light (BL) receptor phototropin (phot) is specifically found in green plants; it regulates various BL-induced responses such as phototropism, chloroplast movement, stomatal opening, and leaf flattenin...

    Kazuhiro Ishishita, Noriyuki Suetsugu, Yuki Hirose in Journal of Plant Research (2016)

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    Article

    Clinical course of juvenile myelomonocytic leukemia in the blast crisis phase treated by acute myeloid leukemia-oriented chemotherapy and allogeneic hematopoietic stem cell transplantation

    Juvenile myelomonocytic leukemia (JMML) is a mixed myeloproliferative and myelodysplastic disorder that occurs in early childhood. The clinical course of JMML is highly variable. A third of patients follow a r...

    Satoshi Ueda, Naoki Sakata, Hideki Muramatsu in International Journal of Hematology (2014)

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    Article

    l-Asparagine depletion levels and l-asparaginase activity in plasma of children with acute lymphoblastic leukemia under asparaginase treatment

    To determine the minimum levels of l-asparaginase (ASNase) activity necessary to maintain l-asparagine (Asn) depletion under ASNase treatment in acute lymphoblastic leukemia (ALL).

    Masahito Tsurusawa, Motoaki Chin, Asayuki Iwai in Cancer Chemotherapy and Pharmacology (2004)