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Open AccessA comprehensive analysis of novel disulfide bond introduction site into the constant domain of human Fab
Generally, intermolecular disulfide bond contribute to the conformational protein stability. To identify sites where intermolecular disulfide bond can be introduced into the Fab’s constant domain of the therap...
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Article
Role of the osmolyte taurine on the folding of a model protein, hen egg white lysozyme, under a crowding condition
Taurine is one of the osmolytes that maintain the structure of proteins in cells exposed to denaturing environmental stressors. Recently, cryoelectron tomographic analysis of eukaryotic cells has revealed that...
