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  1. No Access

    Article

    IgA-Nephropathie

    Die IgA(Immunglobulin A)-Nephropathie (IgAN) ist die häufigste primäre Glomerulonephritisform in der westlichen Welt. Während bei 30 % der Patienten eine spontane Remission eintreten kann, sind weitere 20–30 %...

    C. Seikrit, T. Rauen, Prof. Dr. J. Floege in Der Nephrologe (2020)

  2. No Access

    Article

    Immunglobulin-A-Nephropathie

    Die Immunglobulin-A-Nephropathie (IgAN) ist die häufigste primäre Glomerulonephritisform in der westlichen Welt. Die pathogenetische Bedeutung von autoimmunen Mechanismen, Genetik und Umwelt- bzw. Ernährungsfa...

    C. Seikrit, T. Rauen, Prof. Dr. J. Floege in Der Internist (2019)

  3. Article

    Open Access

    Stat3 and Stat5 govern IL-10 expression in T cells through trans-activation and epigenetic remodelling in health and disease

    CM Hedrich, T Rauen, JC Crispin, GC Tsokos in Molecular and Cellular Pediatrics (2014)

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    Article

    A novel isoform of the orphan receptor RORγt suppresses IL-17 production in human T cells

    T helper (Th)17 cells constitute a distinct subset of CD4+ helper T cells that is mainly characterized by abundant interleukin (IL)-17 production and is involved in the host defence against bacteria and fungi as ...

    T Rauen, Y-T Juang, C M Hedrich, K Kis-Toth, G C Tsokos in Genes & Immunity (2012)

  5. No Access

    Article

    Electrogenic Glutamate Transporters in the CNS: Molecular Mechanism, Pre-steady-state Kinetics, and their Impact on Synaptic Signaling

    Glutamate is the major excitatory neurotransmitter in the mammalian CNS. The spatiotemporal profile of the glutamate concentration in the synapse is critical for excitatory synaptic signalling. The control of ...

    C. Grewer, T. Rauen in The Journal of Membrane Biology (2005)

  6. No Access

    Article

    Diversity of glutamate transporter expression and function in the mammalian retina

    Glutamate is the major excitatory neurotransmitter of the mammalian retina and glutamate uptake is essential for normal transmission at glutamatergic synapses.

    T. Rauen in Amino Acids (2000)

  7. No Access

    Article

    High-affinity glutamate transporters in the rat retina: a major role of the glial glutamate transporter GLAST-1 in transmitter clearance

    Glutamate is the major excitatory neurotransmitter of the mammalian retina and glutamate uptake is essential for normal transmission at glutamatergic synapses. The reverse transcriptase-polymerase chain reacti...

    T. Rauen, W. Rowland Taylor, Kirsten Kuhlbrodt… in Cell and Tissue Research (1997)

  8. No Access

    Article

    Differential expression of three glutamate transporter subtypes in the rat retina

    The immunocytochemical distribution of the three excitatory amino acid transporter subtypes GLT-1, GLAST-1 and EAAC-1 was studied in the rat retina using antibodies raised against synthetic peptides correspond...

    T. Rauen, J. D. Rothstein, H. Wässle in Cell and Tissue Research (1996)

  9. No Access

    Chapter and Conference Paper

    Myelin and Myelin-Forming Cells in the Brain of Fish — A Cell Culture Approach

    Myelin is an extension of the glial plasma membrane which is wrapped around nerve fibers in a typical multilamellar fashion. The occurence of densely compacted myelin around axons is a characteristic feature c...

    G. Jeserich, T. Rauen, A. Stratmann in Cellular and Molecular Biology of Myelination (1990)