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  1. Article

    Open Access

    Immunoscore and Immunoprofiling in cancer: an update from the melanoma and immunotherapy bridge 2015

    The fifth “Melanoma Bridge Meeting” took place in Naples, December 1–5th, 2015. The main topics discussed at this meeting were: Molecular and Immuno advances, Immunotherapies and Combination Therapies, Tumor M...

    J. Galon, B. A. Fox, C. B. Bifulco, G. Masucci, T. Rau… in Journal of Translational Medicine (2016)

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  2. Article

    Open Access

    Overexpression of TACE and TIMP3 mRNA in head and neck cancer: association with tumour development and progression

    TACE/ADAM17 is a transmembranous protease that cleaves membrane-bound growth factors like EGFR ligands. TACE-dependent proteolysis is regulated by its inhibitor, tissue inhibitor of metalloproteinases 3 (TIMP3...

    J-W Kornfeld, S Meder, M Wohlberg, R E Friedrich, T Rau… in British Journal of Cancer (2011)

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  3. No Access

    Article

    Differenzialdiagnostik erblicher Dickdarmkarzinomsyndrome

    Etwa ein Drittel der kolorektalen Karzinome (KRK) treten familiär gehäuft auf, wobei etwa 5% einen monogenetischen Erbgang aufweisen. Diagnostisch hilfreich ist die Unterscheidung zwischen Erkrankungen mit und...

    Prof. Dr. J. Rüschoff, E. Heinmöller, A. Hartmann, R. Büttner, T. Rau in Der Pathologe (2010)

  4. No Access

    Article

    Pharmacogenetic characteristics of patients with complicated phenprocoumon dosing

    Anticoagulation therapy with coumarins necessitates a strict individualization of dosing. Whereas the impacts of the cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) polymorphisms on warfarin...

    D. Werner, U. Werner, A. Wuerfel, A. Grosch… in European Journal of Clinical Pharmacology (2009)

  5. No Access

    Article

    Do K-wires made from shape memory alloys increase pull-out forces? A preliminary experimental cadaver study in bovine bone

    After osteosynthesis of the proximal humerus by Kirschner wires (K-wire), loosening and secondary loss can occur. This study tested primary fixation of wires made from a shape memory alloy (SMA) Nitinol® (NiTi...

    U. Wiebking, T. Gösling, W. Monschizada… in Medical & Biological Engineering & Computi… (2007)

  6. No Access

    Chapter

    Transfection studies using a new cardiac 3D gel system

    This paper summarizes recent progress in reconstituting embryonic chick or neonatal rat cardiac myocytes to a 3-dimensional heart tissue-like structure (“engineered heart tissue”, EHT). The EHT is anchored to ...

    T. Eschenhagen, C. Fink, T. Rau, U. Remmers… in Molecular Approaches to Heart Failure Ther… (2000)

  7. No Access

    Article

    Identification of motility factors produced by rat and human mammary carcinoma cells

    H. Kopdag, U. Scherdin, T. Rau, F. Hölzel in Journal of Cancer Research and Clinical On… (1995)

  8. No Access

    Article

    Epithelial cells in nerve-free hydra produce morphogenetic substances

    It has been shown that hydra, consisting almost exclusively of epithelial cells, have normal morphogenetic properties. This means that they are able to reproduce asexually by budding and to regenerate head or ...

    H. C. Schaller, T. Rau, H. Bode in Nature (1980)