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Article
Mesorectal failure after chemoradiotherapy for squamous cell carcinoma of the anus: is sphincter-saving surgery reasonable?
Abdominoperineal resection (APR) is today the standard treatment for improving survival in case of mesorectal failure without anal canal recurrence after chemoradiotherapy (CRT) for squamous cell carcinoma of ...
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Article
Open AccessThe sound of a Martian dust devil
Dust devils (convective vortices loaded with dust) are common at the surface of Mars, particularly at Jezero crater, the landing site of the Perseverance rover. They are indicators of atmospheric turbulence an...
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Open AccessAuthor Correction: In situ recording of Mars soundscape
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Open AccessIn situ recording of Mars soundscape
Before the Perseverance rover landing, the acoustic environment of Mars was unknown. Models predicted that: (1) atmospheric turbulence changes at centimetre scales or smaller at the point where molecular visco...
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Open AccessMulti-model Meteorological and Aeolian Predictions for Mars 2020 and the Jezero Crater Region
Nine simulations are used to predict the meteorology and aeolian activity of the Mars 2020 landing site region. Predicted seasonal variations of pressure and surface and atmospheric temperature generally agree...
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Article
Mars’ Background Free Oscillations
Observations and inversion of the eigenfrequencies of free oscillations constitute powerful tools to investigate the internal structure of a planet. On Mars, such free oscillations can be excited by atmospheri...
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Open AccessConformations of tissue plasminogen activator (tPA) orchestrate neuronal survival by a crosstalk between EGFR and NMDAR
Tissue-type plasminogen activator (tPA) is a pleiotropic serine protease of the central nervous system (CNS) with reported neurotrophic and neurotoxic functions. Produced and released under its single chain fo...
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Unveiling an exceptional zymogen: the single-chain form of tPA is a selective activator of NMDA receptor-dependent signaling and neurotoxicity
Unlike other serine proteases that are zymogens, the single-chain form of tissue plasminogen activator (sc-tPA) exhibits an intrinsic activity similar to that of its cleaved two-chain form (tc-tPA), especially...
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Article
Dynamics of drop formation in granular suspensions: the role of volume fraction
The presence of grains strongly modifies the detachment of drops of a viscous liquid. We have shown previously that the detachment of drops of granular suspensions takes place via different regimes (Bonnoit et...