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Article
Changes in cerebral blood flow in Asperger syndrome during theory of mind tasks presented by the auditory route
Lack of theory of mind (ToM) has been considered to be a key feature in Asperger syndrome (AS). The main aim of the present study was to determine whether an exclusively auditory input of ToM stories activate...
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Article
A case of Salla disease with involvement of the cerebellar white matter
Salla disease (SD) is a lysosomal disorder manifesting in infancy with hypotonia, nystagmus, ataxia and retarded motor development. MRI typically shows hypomyelination confined to the cerebral white matter. We...
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Article
Neuronal ceroid lipofuscinoses in childhood
NCL disorders are progressive brain diseases with an autosomal recessive inheritance in all eleven childhood types. These occure world-wide but may be enriched in some countries. In Finland altogether about 4...
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Article
Atypical juvenile neuronal ceroid liposfuscinosis with granular osmiophilic deposit-like inclusions in the autonomic nerve cells of the gut wall
In this 8-year-old boy, who had been exposed to alcohol and oxazepam during pregnancy, visual failure was the first symptom of a neuronal ceroid lipofuscinosis (NCL) disorder, noticed at the age of 5 years. O...
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Article
MRI of the brain in neurologically healthy middle-aged and elderly individuals
Our purpose was to document the MRI appearances of the brain in healthy middle-aged to elderly subjects. T2- and proton density-weighted axial slices were obtained in 61 volunteers, 30–86 years of age. After ...
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Article
MRI of neuronal ceroid lipofuscinosis. II. Postmortem MRI and histopathological study of the brain in 16 cases of neuronal ceroid lipofuscinosis of juvenile or late infantile type
Postmortem MRI was carried out on the formalin-fixed brains of 14 patients with juvenile (JNCL) and two with late infantile neuronal ceroid lipofuscinosis, one of variant and the other of classical type. Two ...
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Article
MRI of neuronal ceroid lipofuscinosis
We studied 30 patients with juvenile neuronal ceroid lipofuscinosis (JNCL). The patients (aged 6–25 years) and 43 age-matched healthy volunteers underwent MRI. After visual assessment, the signal intensity was...
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Article
MRI of the normal brain from early childhood to middle age
The magnetic resonance images of 67 healthy subjects aged 4–50 years were studied for differences in general signal intensity between the different brain structures, the frequency of focal intensity changes in...
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Article
MRI of the normal brain from early childhood to middle age
We examined 66 healthy volunteers aged 4 to 50 years by magnetic resonance imaging (MRI) and the signal intensity was measured on T2-weighted images in numerous sites and correlated with age and sex. Using dis...
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Article
The normal brain stem from infancy to old age
Our purpose was to develop a method of measuring the size of the brain stem by routine MRI and to determine brain stem dimensions in a normal population. We examined 174 subjects, aged 4 months to 86 years, wi...
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Article
Early juvenile neuronal ceroid-lipofuscinosis or variant Jansky-Bielschowsky disease: Diagnostic criteria and nomenclature