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Article
New scattering formula for the analysis of X-ray line broadening by composition profiles
The variation of the lattice constantsa i (i=1,2,3) with the depthR in a crystalline solid leads to broadening of the x-ray reflections. The broadening is calculated for polycry...
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Article
The effect of two synthetic phospholipids on cell proliferation and phosphatidylcholine biosynthesis in Madin-Darby canine kiney cells
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Article
Yield stress increase in a W/Cu composite observed by neutron diffraction
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Article
Relapse in childhood acute lymphoblastic leukemia is associated with a decrease of the Bax/Bcl-2 ratio and loss of spontaneous caspase-3 processing in vivo
Dysfunction of the p53/Bax/caspase-3 apoptosis signaling pathway has been shown to play a role in tumorigenesis and tumor progression, ie the development of acquired drug resistance. Low expression of the apop...
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Article
Phonon dispersion and elastic constants in Fe-Cr-Mn-Ni austenitic steel
The lattice dynamics of Fe-18Cr-10Mn-16Ni austenitic steel was studied by inelastic neutron scattering techniques. Phonon dispersion curves were measured in the [100], [011] and [111] directions at low wavevec...
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Article
The kiss of death: promises and failures of death receptors and ligands in cancer therapy
Death receptors and their ligands exert important regulatory functions in the maintenance of tissue homeostasis and the physiological regulation of programmed cell death. Currently, six different death recepto...
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Article
Piceatannol, a hydroxylated analog of the chemopreventive agent resveratrol, is a potent inducer of apoptosis in the lymphoma cell line BJAB and in primary, leukemic lymphoblasts
The stilbene phytochemicals resveratrol and piceatannol have been reported to possess substantial antitumorigenic and antileukemic activities, respectively. Although recent experimental data revealed the proap...
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Article
Bax expression correlates with cellular drug sensitivity to doxorubicin, cyclophosphamide and chlorambucil but not fludarabine, cladribine or corticosteroids in B cell chronic lymphocytic leukemia
In B-CLL, non-proliferating B cells accumulate due to defective apoptosis. Cytotoxic therapies trigger apoptosis and deregulation of apoptotic pathways contributes to chemoresistance. Loss of the apoptosis-pro...
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Article
Phonon dispersion in austenitic stainless steel Fe18Cr12Ni2Mo
The phonon dispersion of Fe18Cr12Ni2Mo austenitic stainless steel was measured along the symmetry directions [001], [110] and [111]. Data were analysed in the frame of the Born–von Karman model of lattice dyna...
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Article
Cation channels trigger apoptotic death of erythrocytes
Erythrocytes are devoid of mitochondria and nuclei and were considered unable to undergo apoptosis. As shown recently, however, the Ca2+-ionophore ionomycin triggers breakdown of phosphatidylserine asymmetry (lea...
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Article
Inhibition of erythrocyte cation channels and apoptosis by ethylisopropylamiloride
Even though lacking mitochondria and nuclei erythrocytes do undergo apoptotic cell death which is characterized by breakdown of phosphatidylserine asymmetry (leading to annexin binding), membrane blebbing and ...
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Article
Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes
Erythrocytes lack nuclei and mitochondria, the organelles important for apoptosis of nucleated cells. However, following increase of cytosolic Ca2+ activity, erythrocytes undergo cell shrinkage, cell membrane ble...
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Article
PGE2 in the regulation of programmed erythrocyte death
Hyperosmotic shock, energy depletion, or removal of extracellular Cl− activates Ca2+-permeable cation channels in erythrocyte membranes. Subsequent Ca2+ entry induces erythrocyte shrinkage and exposure of phospha...
