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Article
FADD self-association is required for stable interaction with an activated death receptor
Receptor-mediated programmed cell death proceeds through an activated receptor to which the death adaptor FADD and the initiator procaspases 8 and/or 10 are recruited following receptor stimulation. The adapto...
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Article
Involvement of ceramide in hyperosmotic shock-induced death of erythrocytes
Erythrocytes lack nuclei and mitochondria, the organelles important for apoptosis of nucleated cells. However, following increase of cytosolic Ca2+ activity, erythrocytes undergo cell shrinkage, cell membrane ble...