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    Article

    Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways

    Loss of tumour suppressor gene function can occur as a result of epigenetic silencing of large chromosomal regions, referred to as long-range epigenetic silencing (LRES), and genome-wide analyses have revealed...

    A R Dallosso, B Øster, A Greenhough, K Thorsen, T J Curry, C Owen, A L Hancock… in Oncogene (2012)