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  1. No Access

    Article

    Long-range epigenetic silencing of chromosome 5q31 protocadherins is involved in early and late stages of colorectal tumorigenesis through modulation of oncogenic pathways

    Loss of tumour suppressor gene function can occur as a result of epigenetic silencing of large chromosomal regions, referred to as long-range epigenetic silencing (LRES), and genome-wide analyses have revealed...

    A R Dallosso, B Øster, A Greenhough, K Thorsen, T J Curry, C Owen, A L Hancock… in Oncogene (2012)

  2. Article

    Open Access

    Repression of KIAA1199 attenuates Wnt-signalling and decreases the proliferation of colon cancer cells

    The KIAA1199 transcript is upregulated in colon adenomas and downregulated upon β-catenin knockdown.

    K Birkenkamp-Demtroder, A Maghnouj, F Mansilla, K Thorsen… in British Journal of Cancer (2011)

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