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Article
Open AccessLongitudinal trajectories of anterior cingulate glutamate and subclinical psychotic experiences in early adolescence: the impact of bullying victimization
Previous studies reported decreased glutamate levels in the anterior cingulate cortex (ACC) in non-treatment-resistant schizophrenia and first-episode psychosis. However, ACC glutamatergic changes in subjects ...
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Article
Open AccessUrinary exosomal microRNAs as predictive biomarkers for persistent psychotic-like experiences
Psychotic-like experiences (PLEs) occur occasionally in adolescence and mostly disappear with increasing age. Their presence, if persistent, is considered a robust risk factor for subsequent psychiatric disord...
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Article
Open AccessHair zinc levels and psychosis risk among adolescents
Recent meta-analyses have shown lower zinc and higher copper levels in the serum of people with schizophrenia than in healthy controls. However, the relationship between trace elements (TEs) and the pathophysi...
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Article
Open AccessRole of advanced glycation end products in the longitudinal association between muscular strength and psychotic symptoms among adolescents
Muscular strength, assessed by handgrip, is a risk indicator for psychiatric disorders, including psychosis. However, the biological mechanisms underlying this association remain unclear. Since advanced glycat...
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Article
Open AccessFingertip advanced glycation end products and psychotic symptoms among adolescents
Case control studies have suggested that advanced glycation end products play a key role in the pathophysiology of chronic schizophrenia. However, the longitudinal association between advanced glycation end pr...
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Article
Open AccessAbnormal asymmetries in subcortical brain volume in early adolescents with subclinical psychotic experiences
Subcortical structures may have an important role in the pathophysiology of psychosis. Our recent mega-analysis of structural magnetic resonance imaging (MRI) data has reported subcortical volumetric and later...
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Article
Open AccessComprehensive early intervention for patients with first-episode psychosis in Japan (J-CAP): study protocol for a randomised controlled trial
Comprehensive approaches for patients with psychotic symptoms play essential roles in the symptomatic and functional outcomes of patients, especially during disease onset. In Japan, the shortage of mental heal...