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Article
Open AccessDiagnosis of paediatric tuberculosis by optically detecting two virulence factors on extracellular vesicles in blood samples
Sensitive and specific blood-based assays for the detection of pulmonary and extrapulmonary tuberculosis would reduce mortality associated with missed diagnoses, particularly in children. Here we report a nano...
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Article
Open AccessEvaluation of a serum-based antigen test for tuberculosis in HIV-exposed infants: a diagnostic accuracy study
Non-sputum methods are urgently needed to improve tuberculosis diagnosis and treatment monitoring in children. This study evaluated the ability of a serum assay quantifying a species-specific peptide of the Mycob...
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Article
Open AccessPulmonary tuberculosis screening in anti-retroviral treated adults living with HIV in Kenya
People living with HIV (PLHIV) who reside in high tuberculosis burden settings remain at risk for tuberculosis disease despite treatment with anti-retroviral therapy and isoniazid preventive therapy (IPT). The...