6 Result(s)
within
Suzan Wopereis
Life Sciences
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Article
Analyzing metabolomics-based challenge tests
Challenge tests are used to assess the resilience of human beings to perturbations by analyzing responses to detect functional abnormalities. Well known examples are allergy tests and glucose tolerance tests. ...
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Article
Semi-targeted metabolomic approaches to validate potential markers of health for micronutrients: analytical perspectives
Recommended dietary allowances for micronutrients fluctuate noticeably within European Union countries. The Network of Excellence EURRECA (EURopean micronutrient RECommendations Aligned) aims at harmonising mi...
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Article
Open AccessPlasma metabolomics and proteomics profiling after a postprandial challenge reveal subtle diet effects on human metabolic status
We introduce the metabolomics and proteomics based Postprandial Challenge Test (PCT) to quantify the postprandial response of multiple metabolic processes in humans in a standardized manner. The PCT comprised ...
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Article
Metabolomics of prolonged fasting in humans reveals new catabolic markers
Fasting is one of the simplest metabolic challenges that can be performed in humans. We here report for the first time a comprehensive analysis of the human “fasting metabolome” obtained from analysis of plasm...
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Article
Open AccessMass-spectrometry-based metabolomics: limitations and recommendations for future progress with particular focus on nutrition research
Mass spectrometry (MS) techniques, because of their sensitivity and selectivity, have become methods of choice to characterize the human metabolome and MS-based metabolomics is increasingly used to characteriz...
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Article
Open AccessImproving the analysis of designed studies by combining statistical modelling with study design information
In the fields of life sciences, so-called designed studies are used for studying complex biological systems. The data derived from these studies comply with a study design aimed at generating relevant informat...
