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  1. No Access

    Article

    Handelin extends lifespan and healthspan of Caenorhabditis elegans by reducing ROS generation and improving motor function

    Aging and aging-related disorders contribute to formidable socioeconomic and healthcare challenges. Several promising small molecules have been identified to target conserved genetic pathways delaying aging to...

    Huijie Zhang, Jiawei Qin, **nqiang Lan, Weirong Zeng, **g Zhou… in Biogerontology (2022)

  2. No Access

    Article

    Autophagy and Hsp70 activation alleviate oral epithelial cell death induced by food-derived hypertonicity

    Stable intracellular and intercellular osmolarity is vital for all physiological processes. Although it is the first organ that receives food, the osmolarity around the mouth epithelium has never been systemat...

    Ji Yang, Huijie Zhang, Sujiao Sun, Xue Wang, Ying Guan… in Cell Stress and Chaperones (2020)

  3. No Access

    Article

    A high concentration of DMSO activates caspase-1 by increasing the cell membrane permeability of potassium

    Dimethyl sulfoxide (DMSO) is widely used in the laboratory and in clinical situations because it is soluble in both aqueous and organic media and can be used to treat many types of diseases. Thus, it is meanin...

    Yang **ang, Ming-ming Zhao, Sujiao Sun, **ao-Long Guo, Qiquan Wang… in Cytotechnology (2018)

  4. No Access

    Article

    Wild chrysanthemum extract prevents UVB radiation-induced acute cell death and photoaging

    Wild chrysanthemum (Chrysanthemum indicum L.) is traditionally used in folk medicine as an anti-inflammatory agent. It is also used in the southwest plateau region of China to prevent ultraviolet-induced skin dam...

    Sujiao Sun, ** Jiang, Weiting Su, Yang **ang, Jian Li, Lin Zeng… in Cytotechnology (2016)