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Article
Open Access3D simulation of percutaneous sustentaculum tali screw insertion in calcaneal fractures
In calcaneal fractures, the percutaneous screw fixation (PSF) is currently considered to be the better choice, but it is difficult to accurately place the screw into the sustentaculum tali (ST) during the oper...
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Article
Population pharmacokinetic analyses of tacrolimus in non-transplant patients: a systematic review
Tacrolimus (TAC) has been increasingly used in patients with non-transplant settings. Because of its large between-subject variability, several population pharmacokinetic (PPK) studies have been performed to f...
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Article
Dual-omics reveals temporal differences in acute sympathetic stress-induced cardiac inflammation following α1 and β-adrenergic receptors activation
Sympathetic stress is prevalent in cardiovascular diseases. Sympathetic overactivation under strong acute stresses triggers acute cardiovascular events including myocardial infarction (MI), sudden cardiac deat...
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Article
Open AccessMelanin-like polydopamine nanoparticles mediating anti-inflammatory and rescuing synaptic loss for inflammatory depression therapy
Inflammatory depression is closely related to neuroinflammation. However, current anti-inflammatory drugs have low permeability to cross blood–brain barrier with difficulties reaching the central nervous syste...
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Reference Work Entry In depth
Organosulfur Compounds in Food
Sulfur is one of the essential macronutrients and plays critical role in overall health maintenance. Plant-derived organosulfur compounds (OSCs) are the important source of dietary sulfur. Garlic is one of the...
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Article
Nutrients Have a Different Impact on the Salt Tolerance of Two Coexisting Suaeda Species in the Yellow River Delta
Suaeda species are widely distributed in the coastal areas and are commonly selected as candidates for coastal saline–alkaline soil restoration. In this study, a pot experiment was carried out to investigate the ...
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Article
Open AccessA WRKY transcription factor, TaWRKY42-B, facilitates initiation of leaf senescence by promoting jasmonic acid biosynthesis
Leaf senescence comprises numerous cooperative events, integrates environmental signals with age-dependent developmental cues, and coordinates the multifaceted deterioration and source-to-sink allocation of nu...
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Article
Open AccessIdentification and expression of DoCCaMK during Sebacina sp. symbiosis of Dendrobium officinale
Dendrobium officinale Kimura et Migo is a famous precious medicinal plant in China. Seed and seedling were cultivated with the mycorrhizal fungus Sebacina sp. CCaMK was initially cloned from D. officinale based o...
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Living Reference Work Entry In depth
Organosulfur Compounds in Food
Sulfur is one of the essential macronutrients and plays critical role in overall health maintenance. Plant-derived organosulfur compounds (OSCs) are the important source of dietary sulfur. Garlic is one of the...
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Article
Open AccessA comparative study on shared-use medicines in Tibetan and Chinese medicine
Tibetan medicine (TM) and traditional Chinese medicine (TCM) are two independent traditional medical systems. Due to geographical factors, the development of Tibetan medicinal theory is relatively independent,...
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Article
Open AccessPreoperative Heart Rate Variability as Predictors of Vagus Nerve Stimulation Outcome in Patients with Drug-resistant Epilepsy
Vagus nerve stimulation (VNS) is an adjunctive treatment for drug-resistant epilepsy (DRE). However, it is still difficult to predict which patients will respond to VNS treatment and to what extent. We aim to ...
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Article
A high concentration of DMSO activates caspase-1 by increasing the cell membrane permeability of potassium
Dimethyl sulfoxide (DMSO) is widely used in the laboratory and in clinical situations because it is soluble in both aqueous and organic media and can be used to treat many types of diseases. Thus, it is meanin...
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Article
Open AccessStudy on relationship between pollen exine ornamentation pattern and germplasm evolution in flowering crabapple
Pollen ornamentation patterns are important in the study of plant genetic evolution and systematic taxonomy. However, they are normally difficult to quantify. Based on observations of pollen exine ornamentatio...
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Article
Open AccessDifferentiation of the Chinese minority medicinal plant genus Berchemia spp. by evaluating three candidate barcodes
The genus Berchemia comprises important Chinese plants with considerable medicinal value; however, these plants are often misidentified in the herbal medicinal market. To differentiate the various morphotypes of
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Article
Open AccessRevisiting the holographic dark energy in a non-flat universe: alternative model and cosmological parameter constraints
We propose an alternative model for the holographic dark energy in a non-flat universe. This new model differs from the previous one in that the IR length cutoff
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Article
Design, synthesis and antitumor activity of a novel series of PAC-1 analogues
A novel series of first procaspase activating compound(PAC-1) analogues was designed, synthesized and evaluated for antitumor activity towards two cell lines[human promyelocytic leukemia cell line(HL60) and hu...
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Article
Effects of Monogalactoglycerolipid Deficiency and Diacylglycerol Acyltransferase Overexpression on Oil Accumulation in Transgenic Tobacco
Engineering accumulation of triacylglycerol (TAG) in vegetative tissues has been recently proposed as a promising strategy for increasing plant oil production. However, little is known about regulatory mechani...
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Article
Role of telomere dysfunction in cardiac failure in Duchenne muscular dystrophy
Duchenne muscular dystrophy (DMD), the most common inherited muscular dystrophy of childhood, leads to death due to cardiorespiratory failure. Paradoxically, mdx mice with the same genetic deficiency of dystrophi...
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Article
MicroRNA profiles and their control of male gametophyte development in rice
Plant microRNAs (miRNAs) act as negative regulators of gene expression by slicing target transcripts or inhibiting translation. A number of miRNAs play important roles in development. In order to investigate t...
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Article
Characterization of an A-type cyclin-dependent kinase gene from Dendrobium candidum
Cyclin-dependent kinases (CDKs) play an essential role in cell cycle regulation during the embryonic and postembryonic development of organisms. To better understand the molecular mechanisms of CDKs involved i...
