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Article
Comparative Genitourinary Safety of In-class Sodium-Glucose Cotransporter-2 Inhibitors among Patients with Heart Failure with Preserved Ejection Fraction: A Cohort Study
The American Heart Association recommended sodium-glucose cotransporter-2 inhibitors (SGLT2i) for the management of heart failure with preserved ejection fraction (HFpEF). However, little is known about their ...
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Article
“Quit Cold Turkey”: Effects of a Quit-and-Win Smoking Cessation Challenge Offered at Christmas on Abstinence, Daily Cigarette Intake, and Cravings
Quit-and-win contests are one way to motivate smokers to quit smoking. This study assessed whether a quit-and-win contest offered at Christmas time using a turkey as the prize would influence smoking outcomes ...
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Article
Strigolactone breakdown
The levels of plant hormones are broadly determined by their relative rates of biosynthesis and degradation, but a degradation pathway for strigolactones has been missing. Now an enzyme has been discovered tha...
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Article
Open AccessDivergent receptor proteins confer responses to different karrikins in two ephemeral weeds
Wildfires can encourage the establishment of invasive plants by releasing potent germination stimulants, such as karrikins. Seed germination of Brassica tournefortii, a noxious weed of Mediterranean climates, is ...
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Article
Open AccessSLR1 inhibits MOC1 degradation to coordinate tiller number and plant height in rice
The breeding of cereals with altered gibberellin (GA) signaling propelled the ‘Green Revolution’ by generating semidwarf plants with increased tiller number. The mechanism by which GAs promote shoot height has...
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Article
Open AccessRisk of heart failure hospitalization among users of dipeptidyl peptidase-4 inhibitors compared to glucagon-like peptide-1 receptor agonists
Incretin-based therapies including dipeptidyl peptidase-4 (DPP-4) inhibitors and glucagon like peptide-1 (GLP-1) receptor agonists are novel medications for type 2 diabetes management. Several studies have fou...
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Article
Chasing red herrings: Memory of distractors causes fixation in creative problem solving
Two experiments tested the red herring retrieval hypothesis, which states that fixation in creative problem solving is worse when memory for red herrings (i.e., inappropriate or incorrect solutions) is strengt...
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Chapter
Rice Plant Architecture: Molecular Basis and Application in Breeding
Shoot architecture in rice is determined by the number of leaves, stems, and panicles and by their size, shape, and position on the plant. These factors determine the effectiveness of light interception, the d...
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Article
Resistant Hypertension: Mechanisms and Treatment
Emerging evidence suggests that multiple mechanisms may be responsible for the development of treatment-resistant hypertension (TRH). This review aims to summarize recent data on potential mechanisms of resist...
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Article
When Both Sides are Mistaken: Layperson and Legal Professionals’ Misconceptions of Canadian Suspects’ Legal Rights Upon Arrest
Canadian criminal suspects have notably limited access to legal counsel upon arrest compared to suspects in the U.S. Additionally, prior research has shown significant misunderstanding of police warnings infor...
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Protocol
Assaying Germination and Seedling Responses of Arabidopsis to Karrikins
Karrikins are a small family of naturally occurring plant growth regulators present in the smoke and char produced from burning plant material in wildfires. They can stimulate germination of dormant seed and c...
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Article
Patient satisfaction with extended-interval warfarin monitoring
Extended-interval monitoring of warfarin has been proposed to reduce follow-up burden and improve patient satisfaction. We aimed to make an initial assessment of anticoagulation satisfaction before and after a...
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Article
Open AccessStrigolactones redefine plant hormones
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Article
Stereospecificity in strigolactone biosynthesis and perception
Plants produce strigolactones with different structures and different stereospecificities which provides the potential for diversity and flexibility of function.
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Article
Open AccessWhat are karrikins and how were they ‘discovered’ by plants?
Karrikins are a family of compounds produced by wildfires that can stimulate the germination of dormant seeds of plants from numerous families. Seed plants could have ‘discovered’ karrikins during fire-prone t...
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Article
Destabilization of strigolactone receptor DWARF14 by binding of ligand and E3-ligase signaling effector DWARF3
Strigolactones (SLs) are endogenous hormones and exuded signaling molecules in plant responses to low levels of mineral nutrients. Key mediators of the SL signaling pathway in rice include the α/β-fold hydrola...
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Article
Quality of Life in Treatment-Resistant Hypertension
Treatment-resistant hypertension (TRH) is an increasingly common and clinically challenging hypertension phenotype associated with adverse impact on cardiovascular events and death. Recent evidence, although l...
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Chapter
Application of Various Immobilization Techniques for Algal Bioprocesses
Immobilized cells entrapped within a polymer matrix or attached onto the surface of a solid support have advantages over their free-cell counterpart, with easier harvesting of the biomass, enhanced wastewater ...
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Article
Rice cytochrome P450 MAX1 homologs catalyze distinct steps in strigolactone biosynthesis
Biosynthesis of the strigolactones—important plant hormones—has been solved up to carlactone. Biochemical and genetic evidence now demonstrate that homologous enzymes perform two subsequent oxidations, setting...
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Article
Open AccessRegulation of the cholesterol biosynthetic pathway and its integration with fatty acid biosynthesis in the oleaginous microalga Nannochloropsis oceanica
Sterols are vital structural and regulatory components in eukaryotic cells; however, their biosynthetic pathways and functional roles in microalgae remain poorly understood.