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    Article

    Protamine is an inhibitor of angiogenesis

    Protamine is shown to be a specific inhibitor of angiogenesis. The compound inhibits the capillary proliferation observed in embryogenesis, inflammation, certain immune reactions and the growth of solid tumours.

    Stephanie Taylor, Judah Folkman in Nature (1982)

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    Open Access

    Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1

    Impulsivity describes the tendency to act prematurely without appropriate foresight and is symptomatic of a number of neuropsychiatric disorders. Although a number of genes for impulsivity have been identified...

    Bianca Jupp, Silvia Pitzoi, Enrico Petretto, Adam C. Mar in Scientific Reports (2020)

  3. Article

    Open Access

    Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD

    The GGGGCC hexanucleotide repeat expansion mutation in the chromosome 9 open reading frame 72 (C9orf72) gene is a major genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD). In t...

    Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca in Nature Communications (2023)