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  1. Article

    Open Access

    Mutant GGGGCC RNA prevents YY1 from binding to Fuzzy promoter which stimulates Wnt/β-catenin pathway in C9ALS/FTD

    The GGGGCC hexanucleotide repeat expansion mutation in the chromosome 9 open reading frame 72 (C9orf72) gene is a major genetic cause of amyotrophic lateral sclerosis and frontotemporal dementia (C9ALS/FTD). In t...

    Zhefan Stephen Chen, Mingxi Ou, Stephanie Taylor, Ruxandra Dafinca… in Nature Communications (2023)

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  2. Article

    Open Access

    Impulsivity is a heritable trait in rodents and associated with a novel quantitative trait locus on chromosome 1

    Impulsivity describes the tendency to act prematurely without appropriate foresight and is symptomatic of a number of neuropsychiatric disorders. Although a number of genes for impulsivity have been identified...

    Bianca Jupp, Silvia Pitzoi, Enrico Petretto, Adam C. Mar… in Scientific Reports (2020)

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