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  1. Article

    Open Access

    A Predictive Mathematical Modeling Approach for the Study of Doxorubicin Treatment in Triple Negative Breast Cancer

    Doxorubicin forms the basis of chemotherapy regimens for several malignancies, including triple negative breast cancer (TNBC). Here, we present a coupled experimental/modeling approach to establish an in vitro ph...

    Matthew T. McKenna, Jared A. Weis, Stephanie L. Barnes… in Scientific Reports (2017)

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    Article

    Quantitative [18F]FMISO PET Imaging Shows Reduction of Hypoxia Following Trastuzumab in a Murine Model of HER2+ Breast Cancer

    Evaluation of [18F]fluoromisonidazole ([18F]FMISO)-positron emission tomography (PET) imaging as a metric for evaluating early response to trastuzumab therapy with histological validation in a murine model of HER...

    Anna G. Sorace, Anum K. Syed, Stephanie L. Barnes… in Molecular Imaging and Biology (2017)

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    Article

    A novel model-gel-tissue assay analysis for comparing tumor elastic properties to collagen content

    In previous work, a new assay was realized for determining soft-tissue mechanical properties. The method, named the model-gel-tissue (MGT) assay, couples material testing with a finite element model built from...

    Stephanie L. Barnes, Pampee P. Young… in Biomechanics and Modeling in Mechanobiology (2009)